Abstract: An inactivated mycobacteria for oral use in the prevention of tuberculosis, which are administered using a multi-dose regimen and with a reduced time interval between doses, such as to induce a tolerance-building to infection by the tubercle bacillus. The inactivated bacteria can be used with the aforementioned regimen to control the progression of the infection from a latent state to active tuberculosis.
Type:
Grant
Filed:
June 13, 2013
Date of Patent:
February 28, 2017
Assignees:
FUNDACIO INSTITUT PER A LA INVESTIGACIO EN CIENCIES DE LA SALUT “GERMANS TRIAS I PUJOL” (IGTP), CIBER DE ENFERMEDADES RESPIRATORIAS (CIBERES)
Inventors:
Pere-Joan Cardona Iglesias, Cristina Vilaplana Massaguer, Elena Marzo Escartin