Abstract: A method for analysis of 2-D gel images obtained using electrophoresis. More particularly, a molecular block-matching method for establishing the correspondence between protein spots in a diagnostic-test image and protein spots in a reference image. Individual protein spot matching is performed, thereby removing the need for alignment of the entire reference and test images and permitting automatic labeling of individual protein spots. The method for analysis of 2-D gel images is fully automated, thus making it ideally suited for protein information retrieval systems.
Type:
Application
Filed:
April 24, 2012
Publication date:
May 2, 2013
Applicants:
UNIVERSIDADE DE A CORUNA, FUNDACION CHUAC, SERGAS
Inventors:
Alejandro Celestino Pazos Sierra, Julián Alfonso Dorado de la Calle, Francisco Blanco García, Javier Pereira Loureiro, Juan Ramón Rabuñal Dopico, Cristina Ruiz Romero, Jose Antonio Seoane Fernández, Ana Maria Freire Veiga, Enrique Fernández Blanco, Alvaro Rodriguez Tajes, Carlos Fernandez Lozano, Ana Belén Porto Pazos, Cristian Robert Munteanu