Abstract: Conjugates of a polymer having attached thereto an angiogenesis targeting moiety and a therapeutically active agent such as an anti-cancer agent or anti-angiogenesis agent, and processes of preparing same are disclosed. Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of angiogenesis-related medical conditions such as cancer and cancer metastases are also disclosed.
Type:
Application
Filed:
May 21, 2009
Publication date:
November 24, 2011
Applicant:
Fundacion de la Communidad Valenciana Centro de Investigacion principe felipe
Inventors:
Ronit Satchi-Fainaro, Maria Jesus Vincent Docon