Patents Assigned to FUNDACION PABLO CASSARA
  • Use of oligonucleotides for the treatment and prevention of pain
    Patent number: 11510938
    Abstract: Method for preventing or treating neuropathic and/or inflammatory pain, wherein said method comprises administering at least one effective dose of the phosphorothioate oligonucleotide IMT504. The preventive method may be applied to a mammal to be subjected to a medical or surgical intervention, or to a mammal that may be injured performing a risky task (for example, a soldier in a battle) to prevent development of pain after a medical intervention or injury.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: November 29, 2022
    Assignees: Consejo Nacional de Investigaciones Científicas y Técnicas, Fundacion Pablo Cassara, Universidad Austral
    Inventors: Alejandro Daniel Montaner, Marcelo Jose Villar, Pablo Rodolfo Brumovsky, Candelaria Leiguarda, Maria Florencia Coronel, Inelia Mailín Lara Casadei, Sandra Sbrascini
  • USE OF OLIGONUCLEOTIDES FOR THE TREATMENT AND PREVENTION OF PAIN
    Publication number: 20220362279
    Abstract: A method for the treatment of post-surgical pain in a patient. The method includes: a) administering at least one effective dose of the phosphorothioate oligonucleotide IMT504 to a mammal prior the surgery. The oligonucleotide IMT504 has the nucleotide sequence set forth in SEQ ID No. 1 and b) post-surgery administer a suboptimal amount of an opioid.
    Type: Application
    Filed: June 9, 2022
    Publication date: November 17, 2022
    Applicants: CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS, FUNDACION PABLO CASSARA, UNIVERSIDAD AUSTRAL
    Inventors: Alejandro Daniel Montaner, Marcelo Jose Villar, Pablo Rodolfo Brumovsky, Candelaria Leiguarda, Maria Florencia Coronel, Inelia Mailín Lara Casadei, Sandra Sbrascini, Julia Rubione
  • USE OF OLIGONUCLEOTIDES FOR THE TREATMENT AND PREVENTION OF PAIN
    Publication number: 20200155592
    Abstract: Method for preventing or treating neuropathic and/or inflammatory pain, wherein said method comprises administering at least one effective dose of the phosphorothioate oligonucleotide IMT504. The preventive method may be applied to a mammal to be subjected to a medical or surgical intervention, or to a mammal that may be injured performing a risky task (for example, a soldier in a battle) to prevent development of pain after a medical intervention or injury.
    Type: Application
    Filed: November 14, 2019
    Publication date: May 21, 2020
    Applicants: Consejo Nacional de Investigaciones Científicas y Técnicas, FUNDACION PABLO CASSARA, UNIVERSIDAD AUSTRAL
    Inventors: Alejandro Daniel Montaner, Marcelo Jose Villar, Pablo Rodolfo Brumovsky, Candelaria Leiguarda, Maria Florencia Coronel, Inelia Mailín Lara Casadei, Sandra Sbrascini