Abstract: A gold(III) complex, a conjugate of the gold(iII) complex, a pharmaceutical composition comprising the gold(III) complex and uses and a process for preparing the gold(III) complex. The complex comprises a group of (S?C)-cyclometallated gold(III) complexes containing a 1,1-dithio ligand, which exhibit antibacterial activity against multiresistant microorganisms or against biofilm activity or biofilm disruption. The gold(III) complex has efficacy against a variety of microorganisms and low toxicity.
Type:
Application
Filed:
April 29, 2019
Publication date:
June 24, 2021
Applicants:
UNIVERSIDAD DE ALMERIA, Fundacion Privada Instituto DE Salud Global Barcelona
Inventors:
Sara Maria SOTO GONZALEZ, Carlos RATIA LONCAN, Virginio CEPAS LOPEZ, Yuly LOPEZ CUBILLOS, Fernando LOPEZ ORTIZ, Maria Jose IGLESIAS VALDES-SOLIS, Raquel Maria GONZALEZ SOENGAS