Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent comprises an extracellular matrix (ECM) protein carried on a polycarbonate polyurethane matrix, and wherein the agent binds to tumor cells when implanted in a body. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
Type:
Grant
Filed:
April 30, 2015
Date of Patent:
October 30, 2018
Assignees:
FUNDACIÖN PEDRO BARRIÉ DE LA MAZA, CONDO DE FENOSA, SERGAS, UNIVERSITY OF SANTIAGO DE COMPOSTELA, FUNDACION RAMÓN DOMINGUEZ, BIOMERIX CORPORATION
Inventors:
Alexandre De La Fuente Gonzalez, Rafael Lopez, Miguel Abal Posada, Lawrence Patrick Lavelle, Jr.
Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent is a capture agent and/or a chemoattractant for tumor cells. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
Type:
Grant
Filed:
November 26, 2013
Date of Patent:
July 17, 2018
Assignees:
Fundacion Ramon Dominguez, SERGAS
Inventors:
Alexandre de la Fuente Gonzalez, Rafael Lopez, Miguel Abal Posada
Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent an extracellular matrix (ECM) protein carried on a polycarbonate polyurethane matrix. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
Type:
Application
Filed:
April 30, 2015
Publication date:
August 31, 2017
Applicants:
FUNDACIÓN PEDRO BARRIÉ DE LA MAZA, CONDE DE FENOSA, SERGAS, UNIVERSITY OF SANTIAGO DE COMPOSTELA, FUNDACION RAMÓN DOMINGUEZ, BIOMERIX CORPORATION
Inventors:
Alexandre DE LA FUENTE GONZALEZ, Rafael LOPEZ, Miguel Abal POSADA, Lawrence Patrick LAVELLE, Jr.
Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent an extracellular matrix (ECM) protein carried on a polycarbonate polyurethane matrix. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
Type:
Application
Filed:
April 30, 2015
Publication date:
February 23, 2017
Applicants:
Fundacion Pedro Barrie De La Maza,Conde De Fenosa, Sergas, University of Santiago De Compostela, Fundacion Ramon Dominguez, Biomerix Corporation
Inventors:
Alexandre DE LA FUENTE GONZALEZ, Rafael LOPEZ, Miguel Abal POSADA, Lawrence Patrick LAVELLE, JR.