Abstract: The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.
Type:
Grant
Filed:
March 17, 2010
Date of Patent:
August 16, 2016
Assignees:
FUNDACION UNIVERSIDAD DEL NORTE, PONTIFICIA UNIVERSIDAD JAVERIANA
Inventors:
Luis Alejandro Barrera, Eduardo Egea, Johana Espejo, Catalina Sosa, Elkin Navarro, Gloria Garavito, Dary Luz Mendoza, Leonardo Lareo, Luis Miguel Renjifo Martinez
Abstract: A device for controlling the pressure of a gas in a circuit via the generation of bubbles through a liquid, which is used to produce a continuous positive airway pressure (CPAP), is provided. The device includes a container containing a liquid and a bubble tube with one end located outside the liquid connected to a device connected to a patient's respiratory tract and the other end located within the liquid. The device also includes at least one hose for adjusting the level of liquid in the container.
Type:
Grant
Filed:
July 2, 2010
Date of Patent:
November 10, 2015
Assignees:
Fundacion Universidad Del Norte, Socieded Biotecnologia y Bioingenieria Core S.A.
Abstract: A device for sampling, diluting and analyzing particles and substances normally located on surfaces. The device includes a collection system which, through a rotating collecting surface and a scraper gathers the sample. The device also includes a tank-like storage system to store the diluting solution and a dilution chamber that permits the sample to mix with the solution and be diluted. This mixture is subsequently placed in contact with a detection system which is capable of discerning the presence or not of the substance being sampled.
Type:
Grant
Filed:
January 30, 2010
Date of Patent:
January 27, 2015
Assignee:
Fundacion Universidad del Norte
Inventors:
Eduardo Egea Bermejo, Marco Sanjuan Mejia
Abstract: A method and apparatus for on-line measurement and forecasting of a species concentration while a reaction is taking place, based on the measurement of the electrical conductivity of the reacting volume, and using such measurement to evaluate a first mathematical function relating such value to the concentration of the species in the reacting volume. The evaluation of the first mathematical function requires as inputs: electrical conductivity trajectory, time elapsed, and other significant process variables; it generates as outputs the estimated actual species concentration and at least one forecasted concentration value.
Type:
Grant
Filed:
October 29, 2009
Date of Patent:
March 5, 2013
Assignee:
Fundacion Universidad del Norte
Inventors:
Marco E. Sanjuan, Jaime R. Garcia, Jose D. Posada, Pedro J. Villalba
Abstract: The present invention is related to providing a device for sampling, diluting and analyzing particles and substances normally located on surfaces, wherein said device comprises a collection system which, through a rotating collecting surface and a scraper gather the sample. The device also comprises a tank-like storage system to store the diluting solution and a dilution chamber that permits the sample to mix with the solution and be diluted. This mixture is subsequently placed in contact with a detection system which is capable of discerning the presence or not of the substance being sampled.
Type:
Application
Filed:
January 30, 2010
Publication date:
June 28, 2012
Applicant:
FUNDACION UNIVERSIDAD DEL NORTE
Inventors:
Eduardo Egea Bermejo, Marco Sanjuan Mejia
Abstract: The present invention relates to a device for controlling the pressure of a gas in a circuit by means of the generation of bubbles through a liquid, this effect being is used to produce a continuous positive airway pressure (CPAP). The invention comprises a container containing a liquid; a bubble tube with one end located outside the liquid connected to a device connected to a patient's respiratory tract and the other end located within the liquid; and means for adjusting the level of liquid in the container. The device may also comprise, in addition to the aforesaid, means to stabilize the liquid level inside the container, humidifying and heating means located inside the container, and a gas-recycling system that conveys all or a portion of the gases generated in the container towards the humidifying and heating device.
Type:
Application
Filed:
July 2, 2010
Publication date:
June 28, 2012
Applicants:
Socieded Biotecnologia y Bioingenieria Core S.A., Fundacion Universidad Del Norte
Abstract: The invention refers to the design, synthesis and evaluation of 6 synthetic oligopeptides, that have not been previously described, designed from the T and B epitopes of allergens of group I of intradomiciliary mites of the species Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis, which can be used in the immunomodulation of individuals having immunocompetent systems and in the production of IgY polyclonal antibodies. The invention relates to a first method for obtaining a composition of IgY polyclonal antibodies that can be used as a diagnostic reagent having low cost and high reactivity in respect of intradomiciliary mites, and a second method for the detection of mite allergens, using the IgY antibody composition developed in the first method. The invention further relates to the composition of the IgY polyclonal antibodies.
Type:
Application
Filed:
March 17, 2010
Publication date:
May 3, 2012
Applicants:
PONTIFICIA UNIVERSIDAD JAVERIANA, FUNDACION UNIVERSIDAD DEL NORTE