Abstract: New amines having an anti-inflammatory and analgesic activity, represented by the formula: ##STR1## in which X represents a hydrogen or halogen atom such as chlorine, a cyanide or amino group of the formula ##STR2## in which R.sub.1 and R.sub.2 are each a hydrogen atom, or a lower alkyl group, or form with the nitrogen atom a saturated or unsaturated heterocyclic group at C.sub.5 or C.sub.6 which may contain a second hetero atom such as oxygen or nitrogen, n is equal to 1, 2 or 3 and may be equal to 0 when X represents a hydrogen atom, and their addition salts of pharmaceutically acceptable acids.Method of preparing the above compounds from 3-chloro 4-cyclohexyl acetophenone, which is transformed into 3-chloro 4-cyclohexyl.alpha.-methyl benzylamine, which is then condensed with an amine of the formula X--(CH.sub.2)n -- NH.sub.2, in which X and n are above defined.
Type:
Grant
Filed:
October 27, 1971
Date of Patent:
January 18, 1977
Assignee:
Fuveau S.A.
Inventors:
Michele Moreau, Isaac Karadavidoff, Claude Risse