Abstract: Modular building cleanrooms having integrated mechanical rooms with removable, walkable floor panels above their ceilings are disclosed. The attic area above the sealed cleanroom ceiling and below joists of the modular building's frame provides an interstitial volume through which ducts, piping, electrical conduit, etc. run from the mechanical room to dampers, valves, and junctions boxes. The walkable floor panels can be bar grating through which maintenance people can see components below. The floor panels can have individual sections that may be removed for access to the components. Along with walkable floor panels, the modular building roofs can have foldable electrical panelboards that are pre-wired at the factory and then rotated upright once delivered to their destination.

Abstract: A rapidly deployable cleanroom is constructed from multiple modular building sections that are side-by-side and have similarly sized lengths, as well as user-accessible panels in multiple of them for air, water, power, networking, and other utilities at a similar internal location along their lengths. The utility panels can be standardized such that each panel is substantially identical to one another. The modular building sections can be drawn together using tension cables within lateral hollow extruded structural tubes beneath and/or above the cleanroom, the tension system utilizing jackscrews to pull everything tight. Because the utility panels are at the same longitudinal location in the building sections, the joined structure and resulting open space “ballroom” style cleanroom has the utility panels aligned with each other inside the cleanroom.

Abstract: A rapidly deployable cleanroom is constructed from multiple modular building sections that are side-by-side and have similarly sized lengths, as well as user-accessible panels in multiple of them for air, water, power, networking, and other utilities at a similar internal location along their lengths. The utility panels can be standardized such that each panel is substantially identical to one another. The modular building sections can be drawn together using tension cables within lateral hollow extruded structural tubes beneath and/or above the cleanroom, the tension system utilizing jackscrews to pull everything tight. Because the utility panels are at the same longitudinal location in the building sections, the joined structure and resulting open space “ballroom” style cleanroom has the utility panels aligned with each other inside the cleanroom.

Abstract: Modular building cleanrooms having integrated mechanical rooms with removable, walkable floor panels above their ceilings are disclosed. The attic area above the sealed cleanroom ceiling and below joists of the modular building's frame provides an interstitial volume through which ducts, piping, electrical conduit, etc. run from the mechanical room to dampers, valves, and junctions boxes. The walkable floor panels can be bar grating through which maintenance people can see components below. The floor panels can have individual sections that may be removed for access to the components. Along with walkable floor panels, the modular building roofs can have foldable electrical panelboards that are pre-wired at the factory and then rotated upright once delivered to their destination.

Abstract: Biosafety units, methods of making and sealing the same are disclosed herein. The present invention includes a unitary structure able to be validated for pharmaceutical manufacturing comprising: at least one controlled air, sealable, sterilizable cleanroom; a mechanical system room adjacent to and separate from the cleanroom comprising: one or more air handling units that provide conditioned air to the cleanroom; and one or more power busses that provide power to electrical outlets in the cleanroom from two sources, wherein the at least two power supplies are connectable to one or more external electrical power sources; an integrated fire suppression system integral to the cleanroom; and one or more corridor connectors, wherein a corridor can be attached at the corridor connector.

Abstract: Extruded floorboards having integrated standoffs, or legs, to offset them from the ground or floor underneath, are disclosed in which adjacent floorboards share a common leg for standing off. On each side of the cross section of a floorboard, a shorter leg mates with a longer leg of an adjacent floorboard through a tongue & groove. The mated legs are supported by the longer leg and a foot at the bottom of the longer leg. A stiffening rib is included. The longer leg is longer than the shorter leg and stiffening rig by a predetermined distance so as to leave clearance for air bearings or other components underneath an assembled floor.

Abstract: Biosafety units, methods of making and sealing the same are disclosed herein. The present invention includes a unitary structure able to be validated for pharmaceutical manufacturing comprising: at least one controlled air, sealable, sterilizable cleanroom; a mechanical system room adjacent to and separate from the cleanroom comprising: one or more air handling units that provide conditioned air to the cleanroom; and one or more power busses that provide power to electrical outlets in the cleanroom from two sources, wherein the at least two power supplies are connectable to one or more external electrical power sources; an integrated fire suppression system integral to the cleanroom; and one or more corridor connectors, wherein a corridor can be attached at the corridor connector.

Abstract: The present invention includes a removable utility unit and/or removable utility room for providing one or more utilities to at least one of a controlled air, a sealable, a sterilizable, a sanitizable cleanroom comprising: at least one of a utility connection selected from air, water, gas, or electricity; and a substantially hermetic connector between the removable unit and the cleanroom, wherein the at least one of air, water, gas, or electricity are connectable to matching utility inputs in the cleanroom.

Abstract: A method and a connector unit for connecting two or more structures wherein at least one of the two or more structures being connected is a mobile structure validatable for pharmaceutical manufacturing or patient care. The connector unit comprises of an alignment system, a sealing, and a fixation system. The method for using the connector unit comprises of aligning the two or more structures to dock the two or more structures together, sealing the two or more structures, or one or more structures and an environment air tight with a seal or a sealing system, and affixing the two or more structures together to prevent relative movement of the two or more structures, or breakage of the seal or seal system.

Abstract: Biosafety units, methods of making and sealing the same are disclosed herein. The present invention includes a unitary structure able to be validated for pharmaceutical manufacturing comprising: at least one controlled air, sealable, sterilizable cleanroom; a mechanical system room adjacent to and separate from the cleanroom comprising: one or more air handling units that provide conditioned air to the cleanroom; and one or more power busses that provide power to electrical outlets in the cleanroom from two sources, wherein the at least two power supplies are connectable to one or more external electrical power sources; an integrated fire suppression system integral to the cleanroom; and one or more corridor connectors, wherein a corridor can be attached at the corridor connector.

Abstract: Biosafety units, methods of making and sealing the same are disclosed herein. The present invention includes a unitary structure able to be validated for pharmaceutical manufacturing comprising: at least one controlled air, sealable, sterilizable cleanroom; a mechanical system room adjacent to and separate from the cleanroom comprising: one or more air handling units that provide conditioned air to the cleanroom; and one or more power busses that provide power to electrical outlets in the cleanroom from two sources, wherein the at least two power supplies are connectable to one or more external electrical power sources; an integrated fire suppression system integral to the cleanroom; and one or more corridor connectors, wherein a corridor can be attached at the corridor connector.

Abstract: Biosafety units, methods of making, and sealing the same are disclosed herein. The units comprise at least one controlled air, sealable, sterilizable cleanroom; and a mechanical system room adjacent to the cleanroom comprising: at least two air handling units in a support room adjacent the cleanroom that provide redundant air to the cleanroom with at least Class 100,000 air purity, the air handling units connected to a one or more supply ducts to the cleanroom, and an exhaust duct in communication with the cleanroom and the air handling unit exhaust, wherein a pressure gradient is formed between the cleanroom and the exterior of the structure; and at least two power supplies that provide redundant power to electrical outlets in the cleanroom, wherein the at least two power supplies are connectable to one or more external power sources and the structure is pre-validatable or validated for pharmaceutical manufacturing.

Abstract: Biosafety units, methods of making, and sealing the same are disclosed herein. The units comprise at least one controlled air, sealable, sterilizable cleanroom; and a mechanical system room adjacent to the cleanroom comprising: at least two air handling units in a support room adjacent the cleanroom that provide redundant air to the cleanroom with at least Class 100,000 air purity, the air handling units connected to a one or more supply ducts to the cleanroom, and an exhaust duct in communication with the cleanroom and the air handling unit exhaust, wherein a pressure gradient is formed between the cleanroom and the exterior of the structure; and at least two power supplies that provide redundant power to electrical outlets in the cleanroom, wherein the at least two power supplies are connectable to one or more external power sources and the structure is pre-validatable or validated for pharmaceutical manufacturing.

Abstract: Biosafety units, methods of making, and sealing the same are disclosed herein. The units comprise at least one controlled air, sealable, sterilizable cleanroom; and a mechanical system room adjacent to the cleanroom comprising: at least two air handling units in a support room adjacent the cleanroom that provide redundant air to the cleanroom with at least Class 100,000 air purity, the air handling units connected to a one or more supply ducts to the cleanroom, and an exhaust duct in communication with the cleanroom and the air handling unit exhaust, wherein a pressure gradient is formed between the cleanroom and the exterior of the structure; and at least two power supplies that provide redundant power to electrical outlets in the cleanroom, wherein the at least two power supplies are connectable to one or more external power sources and the structure is pre-validatable or validated for pharmaceutical manufacturing.