Patents Assigned to GÉNÉTHON
  • Methods of increasing efficiency of vector penetration of target tissue
    Patent number: 9546112
    Abstract: Methods for increasing the efficiency of target tissue penetration of an adeno-associated virus (AAV) vector in a patient are provided. In some aspects, the methods involve inhibiting the interaction of the serum protein galectin 3 binding protein (G3BP) with AAV vector. Further provided are methods for reducing tissue distribution of a virus or for neutralizing a virus harbored by an organ destined for transplant, or newly transplanted, by administering a composition comprising G3BP.
    Type: Grant
    Filed: March 22, 2011
    Date of Patent: January 17, 2017
    Assignees: ASSOCIATION INSTITUT DE MYOLOGIE, GÉNÉTHON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6), INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE
    Inventors: Thomas Voit, Luis Garcia, Jérôme Denard, Fedor Svinartchouk