Patents Assigned to Gacell Laboratories AB
  • Controlled release morphine preparation
    Patent number: 5520931
    Abstract: The present invention concerns an oral morphine preparation having essentially complete bioavailability and, for the major part of the dissolution, an essentially zero order and essentially pH independent release of morphine for a period of at least 8 hours, preferably at least 12 hours, during which a period less than 100% is dissolved. In the preparation, the morphine, in the form of an easily soluble salt, is present in a combination with a buffering agent in a preparation coated with a diffusion membrane.
    Type: Grant
    Filed: January 4, 1995
    Date of Patent: May 28, 1996
    Assignee: Gacell Laboratories AB
    Inventors: Christiane Persson, Staffan Waxegard, Soren Kulstad, Lennart Frigren