Abstract: Novel means and methods for their use are provided to determine the function of the product(s) of one or more sample nucleic acids. The sample nucleic acids are synthetic oligonucleotides, DNA, or cDNA and encode polypeptides, antisense nucleic acids, or GSEs. The sample nucleic acids are expressed in a host by a vehicle to alter at least one phenotype of the host. The altered phenotype(s) is/are identified as a means to assign a biological function to the product(s) encoded by the sample nucleic acid(s).
Type:
Grant
Filed:
December 21, 2001
Date of Patent:
April 18, 2006
Assignee:
Galapagos Genomics N.V.
Inventors:
Ronald Vogels, Abraham Bout, Helmuth van Es, Govert Schouten
Abstract: Novel means and methods for their use are provided to determine the function of the product(s) of one or more sample nucleic acids. The sample nucleic acids are synthetic oligonucleotides, DNA, or cDNA and encode polypeptides, antisense nucleic acids, or GSEs. The sample nucleic acids are expressed in a host by a vehicle to alter at least one phenotype of the host. The altered phenotype(s) is/are identified as a means to assign a biological function to the product(s) encoded by the sample nucleic acid(s).
Type:
Grant
Filed:
July 21, 1999
Date of Patent:
January 22, 2002
Assignee:
Galapagos Genomics N.V.
Inventors:
Ronald Vogels, Abraham Bout, Helmuth van Es, Govert Schouten