Patents Assigned to Galapagos Sasu
  • Urea derivatives methods for their manufacture and uses thereof
    Patent number: 8247412
    Abstract: The present invention provides compounds of formula (I): in which R1, R?1, R2, R?2, R3, Y and G have the meanings given in the description, to a process for their preparation, their application by way of medicaments, and to pharmaceutical compositions containing them.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: August 21, 2012
    Assignee: Galapagos Sasu
    Inventors: Pierre Deprez, Hélène Jary, Taoues Temal
  • RSPONDIN-3 INHIBITION IN BONE DISORDERS
    Publication number: 20120039912
    Abstract: The present invention relates to uses of antagonists of Rspondin-3 (Rspo3) polypeptides or Rspondin-3 nucleic acids. The invention is based on the demonstration that partial deficiency of Rspo3 leads to a significant increase of bone mass. These results indicate a major role for Rspo3 as a bone anabolic marker or target. Thus, the invention also relates to the use of Rspo3 antagonists in the treatment of osteopenia disorders, particularly in conditions associated with increased bone resorption.
    Type: Application
    Filed: April 13, 2010
    Publication date: February 16, 2012
    Applicants: GALAPAGOS SASU, DEUTSCHES KREBSFORSCHUNGSZENTRUM
    Inventors: Georges Rawadi, Christof Niehrs
  • Urea derivatives, processes for their preparation, their use as medicaments, and pharmaceutical compositions containing them
    Patent number: 7875609
    Abstract: The present invention provides compounds of Formula (I): in which R1, R?1, R2, R?2, R3, and Y have the meanings given in the description are useful in the treatment of conditions susceptible to modulating ion channels, to a process for their preparation, their application by way of medicaments, and to pharmaceutical compositions containing them.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: January 25, 2011
    Assignee: Galapagos Sasu
    Inventors: Hélène Jary, Taoues Temal, Pierre DePrez
  • Methods of Treating Osteoporosis and Secondary Hyperparathyroidism Using 20-Methyl, Gemini Vitamin D3 Compounds
    Publication number: 20090298799
    Abstract: The invention provides for methods of using 20-methyl Gemini vitamin D3 compounds to treat osteoporosis and secondary hyperparathyroidism.
    Type: Application
    Filed: March 23, 2006
    Publication date: December 3, 2009
    Applicants: BioXell S.p.A., Galapagos SASU
    Inventors: Luciano Adorini, Milan R. Uskokovic, Michèle Resche-Rignon