Patents Assigned to GALDERMA RESEARCH AND DEVELOPMENT
  • Excipient preservatives and pharmaceutical compositions comprised thereof
    Patent number: 8758782
    Abstract: Topically applicable pharmaceutical compositions contain at least one pharmaceutically active agent and an effective antimicrobial amount of a preservative excipient mixture and devoid of such amount of known preservative(s) as would otherwise itself impart an effective antimicrobial action thereto.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: June 24, 2014
    Assignee: Galderma Research & Development
    Inventor: Lydie Maitre
  • Skin moisturizing compositions
    Patent number: 8758805
    Abstract: Novel skin moisturizing compositions are applied onto dry skin, particularly mild to moderately dry skin, are non-irritating and contain at least one natural moisturizing factor, butyrospermum parkii, at least one silicone, and Panthenol.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: June 24, 2014
    Assignee: Galderma Research & Development
    Inventor: Thierry Rabouille
  • IN VITRO METHOD USING HUMAN SKIN FOR EVALUATING THE INFLUENCE OF ABC TRANSPORTERS
    Publication number: 20140162291
    Abstract: An in vitro method is described that uses full-thickness human skin for evaluating the influence of ABC transporters (such as MDR1, MRP1, MRP2 or BCRP) on the absorption and distribution of topically applied medicinal substances.
    Type: Application
    Filed: June 27, 2012
    Publication date: June 12, 2014
    Applicant: Galderma Research & Development
    Inventor: Hanan Osman-Ponchet
  • COMPOSITIONS COMPRISING A FILLER PRODUCT AND A COMPOUND OF THE TETRACYCLINE FAMILY USED AT A SUBANTIMICROBIAL DOSE
    Publication number: 20140148417
    Abstract: A combination product is described. The combination product can include composition “A”, which can have at least one filler product and a composition “B”, which can have at least one compound of the tetracycline family used at a subantimicrobial dose for the treatment of skin aging and scars. Compositions “A” and “B” can be used simultaneously, separately or sequentially over time. Also described, is a single pharmaceutical composition having, in the same physiologically acceptable medium, at least one filler product and at least one compound of the tetracycline family used at a subantimicrobial dose.
    Type: Application
    Filed: October 24, 2011
    Publication date: May 29, 2014
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventor: Guy Bouvier
  • PHARMACEUTICAL/COSMETIC COMPOSITIONS COMPRISING HYALURONIC ACID AND TREATMENT OF DERMATOLOGICAL CONDITIONS THEREWITH
    Publication number: 20140142062
    Abstract: Pharmaceutical/cosmetic compositions containing a dermatologically effective amount of hyaluronic acid, at least one retinoid and/or salt and/or derivative thereof, at least one oligosaccharide and at least one inhibitor of hyaluronic acid degradation, formulated into a physiologically acceptable medium therefor, are useful for the treatment of wrinkles, fine lines, fibroblast depletions and scars.
    Type: Application
    Filed: December 13, 2013
    Publication date: May 22, 2014
    Applicant: Galderma Research & Development
    Inventors: Marc MOUTET, Jean-Claude YADAN
  • Derivatives of novel peroxides, method of preparation thereof and use thereof in human medicine as well as in cosmetics for the treatment or prevention of acne
    Patent number: 8729312
    Abstract: Compounds of the following general formula (I): are described. Also described, are methods of preparing the compounds and their use in therapeutics.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: May 20, 2014
    Assignee: Galderma Research & Development
    Inventors: Claire Bouix-Peter, Jean-Claude Pascal, Nicolas Rodeville
  • Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders
    Patent number: 8729127
    Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: May 20, 2014
    Assignee: Galderma Research & Development
    Inventors: Michael Graeber, Janusz Czernielewski
  • Method for preparing molecular complexes between adapalene and cyclodextrins
    Patent number: 8716342
    Abstract: A method for preparing molecular complexes between Adapalene and cyclodextrins using the technology of dense fluids under pressure, especially that of CO2 is described.
    Type: Grant
    Filed: April 9, 2010
    Date of Patent: May 6, 2014
    Assignee: Galderma Research & Development
    Inventors: Hubert Lochard, Bernard Freiss
  • Topically applicable compositions for the treatment of keratinization disorders
    Patent number: 8716341
    Abstract: Topical compositions containing from 0.01% to 0.09% by weight of adapalene or salts thereof are useful for the treatment or prevention of keratinization disorders, particularly acne, and additionally contain at least one gelling agent selected from among carbomers, polysaccharides, cellulose and its derivatives, copolymers of acrylate and of alkyl acrylate, copolymers of acrylamide and of sodium acrylamido-2-methylpropanesulfonate, and xanthan gum.
    Type: Grant
    Filed: January 5, 2010
    Date of Patent: May 6, 2014
    Assignee: Galderma Research & Development
    Inventor: Jean-Daniel Doutremepuich
  • Cosmetic/dermatological compositions comprising naphthoic acid compounds and polyurethane polymers
    Patent number: 8709392
    Abstract: Cosmetic/dermatological compositions for topical application and useful for the treatment, e.g., of acne, contain, formulated into a physiologically acceptable medium, at least one naphthoic acid compound and at least one polyurethane polymer or derivative thereof, the at least one naphthoic acid compound being dispersed therein.
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: April 29, 2014
    Assignee: Galderma Research & Development
    Inventors: Claire Mallard, Eve Ferrara
  • Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders
    Patent number: 8703820
    Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthanoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.
    Type: Grant
    Filed: October 12, 2010
    Date of Patent: April 22, 2014
    Assignee: Galderma Research & Development
    Inventors: Michael Graeber, Janusz Czernielewski
  • NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS
    Publication number: 20140107129
    Abstract: Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
    Type: Application
    Filed: December 11, 2013
    Publication date: April 17, 2014
    Applicant: Galderma Research & Development
    Inventors: Laurence CLARY, Sandrine CHAMBON, Laurent CHANTALAT, Carine ROSIGNOLI, Olivier ROYE, Jean-Claude PASCAL, Marlene SCHUPPLI-NOLLET
  • 4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and in cosmetics
    Patent number: 8697726
    Abstract: 4-(azacycloalkyl)benzene-1,3-diol compounds are described corresponding to general formula (I) below: Also described, are compositions including the same, processes for preparation thereof and uses thereof in pharmaceutical or cosmetic compositions to treat pigmentary disorders.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: April 15, 2014
    Assignee: Galderma Research & Development
    Inventors: Jean-Guy Boiteau, Karine Bouquet, Sandrine Talano, Corinne Millois Barbuis
  • METHODS AND COMPOSITIONS FOR SAFE AND EFFECTIVE TREATMENT OF ERYTHEMA
    Publication number: 20140094469
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: December 5, 2013
    Publication date: April 3, 2014
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Michael GRAEBER, Christian LOESCHE, Philip FREIDENREICH, Yin-sang LIU, Matthew James LEONI
  • Combination of compounds for treating or preventing skin diseases
    Patent number: 8669233
    Abstract: A combination of compounds for treating skin diseases and particularly rosacea and ocular rosacea is described. The combination of a compound of the avermectin family or of the mylbemycin family with a compound of the family of the alpha-1 or alpha-2 adrenergic receptor agonists is also described. In addition, a product in the form of a kit including: (a) a first composition containing a compound of the avermectin family or of the mylbemycin family, and (b) a second composition different from the first one and containing a compound of the family of the alpha-1 or alpha-2 adrenergic receptor agonists, as a combination product to be used as a drug for treating and/or preventing skin diseases and particularly rosacea and ocular rosacea, wherein said first and second compositions can be applied simultaneously, separately or with a time delay is described.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: March 11, 2014
    Assignee: Galderma Research & Development
    Inventors: André Jomard, Laurent Fredon, Olivier Roye
  • COMPOSITIONS COMPRISING A FILLER PRODUCT AND AT LEAST ONE BIORESORBABLE AND BIODEGRADABLE SILICA-BASED MATERIAL
    Publication number: 20140065221
    Abstract: A combination product including at least one filler product and at least at least one bioresorbable and biodegradable silica-based material, for treating incontinence or treating aging of the skin and scars. Also, a composition including, in a physiologically acceptable medium, at least one filler product and at least at least one bioresorbable and biodegradable silica-based material.
    Type: Application
    Filed: April 2, 2012
    Publication date: March 6, 2014
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Rosy Eloy, Anders Karlsson
  • Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders
    Patent number: 8653140
    Abstract: Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: February 18, 2014
    Assignee: Galderma Research & Development
    Inventors: Michael Graeber, Janusz Czernielewski
  • COMBINATIONS OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE LESIONS
    Publication number: 20140031427
    Abstract: Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO.
    Type: Application
    Filed: September 26, 2013
    Publication date: January 30, 2014
    Applicant: GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Marie-Line ABOU-CHACRA VERNET, Denis GROSS, Christian LOESCHE, Michel PONCET
  • MODULATORS AND METHODS FOR THE TREATMENT OF ROSACEA
    Publication number: 20140031341
    Abstract: An in vitro method of screening candidate compounds for the preventive or curative treatment of rosacea is described. The method can include determining the capacity of a compound to modulate the expression or activity of the Transient Receptor Potential (TRPs), as well as the use of modulators of the expression or activity of this transcription factor for the treatment of rosacea. The method can also include in vitro diagnosis or prognosis of this pathology.
    Type: Application
    Filed: December 19, 2011
    Publication date: January 30, 2014
    Applicants: UNIVERSITAT MUNSTER, GALDERMA RESEARCH & DEVELOPMENT
    Inventors: Jerome Aubert, Martin Steinhoff
  • Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
    Patent number: 8633196
    Abstract: Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: January 21, 2014
    Assignee: Galderma Research & Development
    Inventors: Laurence Clary, Sandrine Chambon, Laurent Chantalat, Carine Rosignoli, Olivier Roye, Jean-Claude Pascal, Marlène Schuppli-Nollet