Abstract: Cosmetic/pharmaceutical compositions useful for regulating the size of sebaceous glands and, in particular, for inhibiting sebum production, or for treating pathologies entailing an overproduction of sebum, or for treating greasy skin and/or a scalp prone to dandruff, contain thus effective amounts of at least one activator of PPAR type receptors.
Abstract: Sprayable pharmaceutical compositions suited for improved transdermal penetration contain a) at least one bioactive agent, notably at least one derivative of vitamin D, (b) at least one volatile silicone and c) a non-volatile oily phase, formulated into d) a pharmaceutically acceptable vehicle therefor.
Type:
Application
Filed:
May 12, 2006
Publication date:
February 22, 2007
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Abstract: Novel pharmaceutical/cosmetic compositions contain at least one biaromatic ligand activator of a PPAR? receptor, such biaromatic ligand having the structural formula (I): and are well suited, inter alia, for regulating and/or restoring skin lipid metabolism, for treating a wide variety of dermatological afflictions, and for preventing and/or treating the signs of aging and/or dry skin.
Type:
Application
Filed:
August 18, 2006
Publication date:
February 22, 2007
Applicant:
GALDERMA RESEARCH & DEVELOPMENT S.N.C.
Inventors:
Jean-Michel Bernardon, Laurence Clary, Eric Terranova
Abstract: Novel ligand compounds having the structural formula (I): and the salts and optical/geometrical isomers thereof are suited for formulation into pharmaceutical compositions useful in human or veterinary medicine, or, alternatively, into cosmetic compositions.
Type:
Application
Filed:
April 24, 2006
Publication date:
January 4, 2007
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Abstract: Novel ligand compounds that activate RAR receptors have the following structural formula (I): and are suited for formulation into pharmaceutical compositions useful in human or veterinary medicine, or, alternatively, into cosmetic compositions.
Type:
Application
Filed:
April 14, 2006
Publication date:
January 4, 2007
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Abstract: Topically applicable cosmetic/pharmaceutical oil-in-water emulsions, well suited for treating or caring for the skin and/or superficial body growths therefrom, include a discontinuous fatty phase dispersed in a continuous aqueous phase and comprise an effective amount of at least one biologically active agent (A) and an effective amount of an emulsifying system (B) therefor, the at least one biologically active agent (A) being non-solubilized therein in micronized particulate state, at least 80%, numerically, of the micronized particles having diameters ranging from 1 to 10 ?m and at least 50%, also numerically, having diameters of less than 5 ?m.
Type:
Application
Filed:
March 20, 2006
Publication date:
July 20, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Abstract: Compositions in the form of a spray contain a pharmaceutical active agent, at least one volatile silicone and a non-volatile oily phase, formulated into a physiologically acceptable medium, are well suited for improved transdermal administration in cosmetics and dermatology.
Type:
Application
Filed:
December 23, 2005
Publication date:
July 6, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
Type:
Application
Filed:
December 20, 2005
Publication date:
July 6, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Inventors:
Laurence Clary, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel
Abstract: The present invention provides for a method of using adapalene for the maintenance theray of acne vulgaris to prevent acne recurrence or reduce the severity of the acne recurrence.
Type:
Application
Filed:
December 13, 2004
Publication date:
June 15, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Abstract: Polynucleotide probes relating to the FANCC, DAD1, GRIM19 and HADHII genes are useful for characterizing biological samples and for identifying compounds suited for the treatment of psoriasis.
Type:
Application
Filed:
October 14, 2005
Publication date:
June 1, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Inventors:
Valerie Trinquet, Patricia Rossio, Paul Fogel
Abstract: Novel compounds that are ligands of the LXR receptors have the following structural formula (I): and are formulated into pharmaceutical compositions useful in human or veterinary medicine, or alternatively into cosmetic compositions.
Type:
Application
Filed:
August 29, 2005
Publication date:
March 16, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Inventors:
Philippe Diaz, Jean-Michel Bernardon, Etienne Thoreau
Abstract: Novel compounds which modulate PPAR-type receptors have the following general formula (I): and are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology and in the fields of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or are formulated into cosmetic compositions.
Type:
Application
Filed:
August 12, 2005
Publication date:
March 9, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Inventors:
Philippe Diaz, Etienne Thoreau, Isabelle Carlavan, Pascale Mauvais, Johannes Voegel
Abstract: Novel compounds which modulate PPAR-type receptors have the following general formula (I): and are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology and in the fields of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or are formulated into cosmetic compositions.
Type:
Application
Filed:
August 12, 2005
Publication date:
February 16, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Inventors:
Philippe Diaz, Etienne Thoreau, Isabelle Carlavan, Pascale Mauvais, Johannes Voegel
Abstract: Topically applicable, stable and non-irritating aqueous-alcoholic cosmetic/dermatological gels suited for cutaneous depigmentation contain water, at least one alcohol, at least one gelling agent, at least one phenolic compound, at least one retinoid, and, optionally, at least one sunscreen, formulated into a topically applicable, physiologically acceptable medium therefor.
Type:
Application
Filed:
June 13, 2005
Publication date:
February 9, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Abstract: Cosmetic/dermatological compositions useful for the treatment of a variety of dermatological conditions, including keratinization disorders, acne, eczema, psoriasis, etc., comprise an invert emulsion containing at least one active agent sensitive to the presence of water, notably a derivative of vitamin D, and solubilized in a glycolic or hydroglycolic dispersed hydrophilic phase, a lipophilic continuous phase and an emulsifier having an HLB ranging from 2 to 7; these invert emulsions exhibit good stability and avoid crystallization of the active agent and/or chemical degradation thereof.
Type:
Application
Filed:
August 4, 2005
Publication date:
February 9, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Abstract: The invention relates to novel stilbene compounds having the general formula (I): as well as to pharmaceutical compositions for use in human or veterinary medicine, including dermatological, rheumatic, respiratory, cardiovascular and ophthalmic conditions and cosmetic compositions and methods of use thereof.
Type:
Grant
Filed:
October 2, 2003
Date of Patent:
January 31, 2006
Assignee:
Galderma Research & Development, S.N.C.
Inventors:
Jean-Michel Bernardon, Bruno Charpentier
Abstract: The invention concerns novel diarylselenide compounds corresponding to the general formula (I) and the use thereof in pharmaceutical compositions in human or veterinary medicine (in the treatment of dermatological, rheumatic, cardiovascular and ophthalmologic pathologies in particular), or in cosmetic compositions.
Abstract: The invention concerns novel diarylselenide compounds corresponding to formula (I): and the use thereof in pharmaceutical compositions in human or veterinary medicine (in the treatment of dermatological, rheumatic, cardiovascular and ophthalmologic pathologies in particular), or in cosmetic compositions.
Type:
Application
Filed:
September 16, 2005
Publication date:
January 19, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Abstract: Novel polycyclic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
Type:
Application
Filed:
June 10, 2005
Publication date:
January 12, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.
Inventors:
Laurence Clary, Pascal Collette, Michel Rivier, Andre Jomard
Abstract: Topically applicable pharmaceutical gel, cream, lotion, solution or ointment compositions contain synergistically effective amounts of a) calcitriol and b) clobetasol propionate, formulated into a topically applicable, pharmaceutically acceptable medium therefor, and are useful for the treatment of such dermatological afflictions or conditions as psoriasis, atopic dermatitis, contact dermatitis and seborrhoeic dermatitis.
Type:
Application
Filed:
June 17, 2005
Publication date:
January 12, 2006
Applicant:
GALDERMA RESEARCH & DEVELOPMENT, S.N.C.