Abstract: The invention refers to a process for the preparation of a self-dispersing or self-emulsifying tablet, wherein a heated granulation mixture containing an active lipophilic substance and a surfactant is granulated into granules, said granules are cooled to a semi-solid state, said semi-solid granules are mixed with one or more fillers to cover the surface of the granules, distribution, the sieved granules are mixed with tabletting aids, and said mixture is compressed into tablets. The granulation mixture can also contain a lipid and/or filler. The invention also refers to tablets prepared by said processes.
Type:
Grant
Filed:
January 21, 2003
Date of Patent:
September 9, 2008
Assignee:
Galencia AB
Inventors:
Jari Alander, Staffan Norberg, Henri Hansson, Marianne Svärd, Lars Hovgaard