Abstract: Substantially pure peptides containing amino acid residues occurring in amyloid A protein and serum amyloid A protein are disclosed. The peptide compounds may be natural or synthetically derived. It is a characteristic feature of the peptides, regardless of their origin, that the sum of the hydrophilicity values of the respective amino acid residues is greater than or equal to zero. Moreover, specific antisera to these peptides are disclosed.
Type:
Grant
Filed:
February 6, 1986
Date of Patent:
July 5, 1988
Assignee:
Gambro Lumdia AB
Inventors:
Anders O. Grubb, Lennart W. Ljunggren, Helene K. Hansson