Abstract: An implant for ovarian decline is provided. The implant includes at least an engineered ovarian support cell, an extracellular matrix substrate, and a delivery apparatus. In some embodiments, the at least an engineered ovarian support cell includes an engineered granulosa cell. In other embodiments, the at least an engineered ovarian support cell includes an engineered lutein cell. In other embodiments, the at least an engineered ovarian support cell includes an engineered theca cell.

Abstract: An implant for ovarian decline is provided. The implant includes at least an engineered ovarian support cell an extracellular matrix substrate, and a delivery apparatus. In some embodiments, the at least an engineered ovarian support cell includes an engineered granulosa cell. In other embodiments, the at least an engineered ovarian support cell includes an engineered lutein cell. In other embodiments, the at least an engineered ovarian support cell includes an engineered theca cell.

Abstract: A platform and method for determining critical transcription factors for TF-based hiPSC differentiation. The platform including: a transcriptomic dataset database; at least a processor; a memory communicatively connected to the processor, the memory containing instructions configuring the at least a processor to generate gene regulatory networks from transcriptomic datasets; determine a candidate transcription factor; analyze an impact of the candidate transcription factor in germline cell development; and output a set of critical transcription factors.

Abstract: An apparatus and method for oocyte rescue in vitro post stimulation, the apparatus including a computing device, wherein the computing device includes at least a processor; and a memory communicatively connected to the at least processor, the memory containing instructions configuring the at least processor to: receive biological sample data from a biological sample relating to a user, including at least an oocyte; determine a maturity level of the at least an oocyte; assign the at least an oocyte to a culture protocol as a function of the maturity level; receive culture data relating to the at least an oocyte as a function of the culture protocol; and calculate a scoring metric as a function of the culture data.