Abstract: A sand screen for installation in a well includes a flow-through element having a center line running in the longitudinal direction of the flow-through element; and a filtration device. The flow-through element has an internal cavity extending over at least parts of a length of the flow-through element. There are a plurality of openings over the length of the flow-through element. The openings, via the filtration device, provide communication between an outer surface of the flow-through element and the internal cavity. The sand screen is flexible in a radial direction and in an axial direction.

Abstract: A sand screen for installation in a well includes a flow-through element having a center line running in the longitudinal direction of the flow-through element; and a filtration device. The flow element has an internal cavity extending over at least parts of a length of the flow-through element. The flow element further has a plurality of openings over the length thereof. The openings, via the filtration device, provide communication between an outer surface of the flow element and the internal cavity. The sand screen is flexible in a radial direction and in an axial direction.

Abstract: The present invention relates to a chimeric protein containing an intramolecular chaperone (IMC) like sequence linked to a target protein, preferably an insulin precursor. The present invention also relates to a process for obtaining a correctly folded insulin-precursor-contain chimeric protein, comprising, inter alia, contacting an incorrectly folded chimeric protein containing an IMC like sequence linked to an insulin precursor with at least one chaotropic auxiliary agent. The present invention further relates to an assay for screening an amino acid sequence for the ability to improve folding of an insulin precursor using a chimeric protein containing an IMC like sequence linked to an insulin precursor.

Abstract: The present invention relates to a chimeric protein containing an intramolecular chaperone (IMC) like sequence linked to a target protein, preferably an insulin precursor. The present invention also relates to a process for obtaining a correctly folded insulin-precursor-containing chimeric protein, comprising, inter alia, contacting an incorrectly folded chimeric protein containing an IMC like sequence linked to an insulin precursor with at least one chaotropic auxiliary agent. The present invention further relates to an assay for screening an amino acid sequence for the ability to improve folding of an insulin precursor using a chimeric protein containing an IMC like sequence linked to an insulin precursor.