Abstract: Spilanthol, in the form of an Acmella oleracea extract, inhibits contractions in subcutaneous muscles, notably those of the face, and can be used as an anti-wrinkle product. A cosmetic treatment procedure for wrinkles consists of locally or subcutaneously applying an effective quantity of a composition based on spilanthol pure or in the form of an Acmella oleracea extract.

Abstract: A caper flower bud extract is obtained by supercritical fluid extraction. The supercritical fluid preferably contains carbon dioxide and at least one cosolvent. A cosmetic composition contains between 0.1 and 10% of the extract.

Abstract: A pharmaceutical composition for oral use is disclosed. It includes, as active principle, a drug liable to undergo a strong first intestinal passage effect and a carrier which is self-micro-emulsifying on contact with an aqueous phase.

Abstract: An aqueous extract of walnut seed meal useful in cosmetic and dermatologic compositions is disclosed. The extract is obtained by macerating the pressed seed meal from Juglans sp. in water and concentrating the water.

Abstract: The invention concerns a method for making tablets with active principle sustained-release which consists in: preparing a fluid oil-in-water emulsion; spraying the resulting emulsion on a powder mixture containing at least the active principle; subjecting said treated powder to a compressing step, to obtain tablets.

Abstract: The invention relates to a process for the manufacture of a pharmaceutical composition with modified release of active principle comprising at least one active principle, a lipid matrix agent composed of ester of alcohol with at least one fatty acid and at least one adjuvant. This process is characterized in that: a powder composed of at least one component selected in the group comprising the active principle and the adjuvant, is mixed, while heating and fluidizing, in order to obtain individual grains; the said lipid matrix agent is liquefied separately under warm conditions; the said powder is then coated under warm conditions by spraying the said lipid matrix agent over the individual grains; finally, the temperature of the combined product is lowered in order to allow the lipid matrix agent to solidify.

Abstract: Composition for pharmaceutical or cosmetic use, capable of providing enhanced bioavailability when ingested, comprising at least a pharmaceutical active ingredient, a lipophilic phase consisting of a mixture of fatty acid esters and glycerides, a surfactant (SA), and a cosurfactant (CoSA). The lipophilic phase consists of a mixture of C8 to C18 polyglycolized glycerides having hydrophilic-lipophilic balance (HLB) of less than 16, this lipophilic phase representing from 32 to 75% of the total weight of the composition. The surfactant (SA) is chosen from the group comprising saturated C8-C10 polyglycolized glycerides and oleic esters of polyglycerol, this surfactant having an HLB of less than 16. The cosurfactant (CoSA) is chosen from the group comprising lauric esters of propylene glycol, oleic esters of polyglycerol and ethyl diglycol. The SA/CoSA ratio is between 0.5 and 6 and the hydrophilic phase of the final microemulsion is supplied after ingestion by the physiological fluid of the digestive milieu.

Abstract: The invention concerns a composition comprising a microemulsion forming system by contact with a hydrophilic phase brought, after ingestion, by the physiological fluid, said microemulsion forming system comprising: at least an active principle; a lipophilic phase; a surfactant (TA); a co-surfactant (CoTA). The invention is characterized in that said composition further comprises an inert polymeric matrix which cannot be ionised at physiological pH, dispersed in the microemulsion forming system before ingestion, said polymeric matrix being capable, after ingestion, of forming on contacting the physiological fluid, a gelled polymeric matrix enabling to release by diffusion, in continuous and prolonged manner the already micro-emulsified active principle.

Abstract: A process for preserving desired characteristics of vegetable plants for cosmetic, condimental, aromatic or food use is described which includes rehydrating harvested vegetable to nearly the water content of freshly harvested plants and then exposing them to microwave radiation to rapidly heat them to the denaturation temperature of the specific enzyme contained in the harvested plants.

Abstract: The invention concerns a method for preparing a modified release of active principle. The method comprises the steps of mixing a powder composed of active principle, adjuvant or combinations thereof while heating and fluidizing in order to obtain individual grains, liquefying a lipid matrix agent composed of partial esters of alcohol with at least one fatty acid, coating the powder by spraying from 1 to 15% by weight of the final composition liquid lipid matrix agent over the individual grains, the spraying air pressure, and optionally the spraying rate varying throughout the coating operation and lowering the temperature of the combined product to allow the lipid matrix agent to solidify around the grains.

Abstract: Composition for pharmaceutical or cosmetic use, capable of forming a microemulsion, comprising at least:an active principle,a lipophilic phase consisting of a mixture of fatty acid esters and glycerides,a surfactant (SA),a cosurfactant (CoSA),a hydrophilic phase,characterized:in that the lipophilic phase consists of a mixture of C.sub.8 to C.sub.18 polyglycolized glycerides having a hydrophilic-lipophilic balance (HLB) of less than 16, this lipophilic phase representing from 30 to 75% of the total weight of the composition;in that the surfactant (SA) is chosen from the group comprising saturated C.sub.8 -C.sub.10 olyglycolized glycerides and oleic esters of polyglycerol, this surfactant having an HLB of less than 16;in that the cosurfactant (CoSA) is chosen from the group comprising lauric esters of propylene glycol, oleic esters of polyglycerol and ethyl diglycol;in that the SA/CoSA ratio is between 0.

Abstract: Improved compositions of benzoyl peroxide are prepared by at least partially dissolving benzoyl peroxide in diethylene glycol monoethyl ether to prepare a premixture which forms a flocculent composition of benzoyl peroxide when admixed with water or an aqueous medium. The improved benzoyl peroxide compositions have a small particle size compared with those prepared by conventional grinding techniques and the time and potential hazards associated with grinding are avoided. The small particle size of the benzoyl peroxide flocculents result in increased surface area of active ingredient on the skin for a given concentration of benzoyl peroxide. The flocculent compositions are used to prepare compositions for the topical treatment of acne or other dermatological disorders.

Abstract: A process for obtaining juices, oils and cakes in stable form by the pressing of fresh plant products is disclosed in which a depressor system in the amount of two to two-and-a-half times the quantity of water contained in the product to be pressed is added to a quantity of crushed product. The depressor system is a mixture of dextrose, saccharose and salt in a proportion by weight of dextrose to saccharose of three times and sugars to salt between seven and seven-and-a-half times. The whole mixture is subjected to exhaustive crushing action to obtain a puree and the puree is then pressed to obtain the juices, oils and cakes in stable form.