Patents Assigned to GB005, INC.
  • Spirocyclic containing compounds and pharmaceutical uses thereof
    Patent number: 10752615
    Abstract: The present invention relates to a novel family of covalent kinases inhibitors, compounds of this class have been found to have inhibitory activity against members of the TEC kinase family, particularly ITK and/or TXK, BTK, TEC and/or combinations thereof. The present invention is directed to a compound of Formula I or pharmaceutically acceptable salt, solvate, solvates of salt, stereoisomer, tautomer, isotope, prodrug, complex or biologically active metabolite thereof, for use in therapy.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: August 25, 2020
    Assignee: GB005, Inc.
    Inventors: Alain Laurent, Stephen J. Morris
  • Benzimidazoles derivatives as Tec kinases family inhibitors
    Patent number: 10562893
    Abstract: The present invention relates to a novel family of covalent kinases inhibitors. Compounds of this class have been found to have inhibitory activity against members of the Tec kinase family, particularly ITK, BTK, BMX, Tec and/or RLK. The present invention is directed to a compound of Formula I or pharmaceutically acceptable salt, solvate, solvate of salt, stereoisomer, tautomer, isotope, prodrug, complex or biologically active metabolite thereof and its use in therapy.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: February 18, 2020
    Assignee: GB005, INC.
    Inventors: Alain Laurent, Yannick Rose, Stephen J. Morris