Abstract: A system and method for providing user interface for user-specified context is disclosed. According to one embodiment, a computer-implemented method for providing a context-based user interface comprises providing a collection of user interface cards based on a user's context and receiving a user's selection of a plurality of user interface cards from the collection of user interface cards. The plurality of user interface cards is saved on a user's device, and the plurality of user interface cards comprises a user interface card that has a data portion and a form portion. The form portion of the user interface card is updated from a card repository. The data portion of the user interface card is separately received from a remote device or a remote server. The user interface card is displayed on the user's device with an updated form portion and the received data portion.

Abstract: Exemplary embodiments are directed to a system and method for estimating and compensating for anode target filtration in an X-ray tube. Certain embodiments record changes in the photon flux over the life of the tube. By comparing the flux values, filtration resulting from a roughened target surface and target deposition on the tube window may be inferred. A plurality of systems and methods for comparing flux values are provided and the relative merits and complementary effects of each discussed.

Abstract: A computer implemented method of analyzing tissue features based on multiplexed biometric images includes storing a data set including cell profile data and an assessment associated with a field of view or a patient. The cell profile data includes biomarker expression intensity data for at least one cell feature. The method includes normalizing the biomarker expression intensity data for each field of view. The method includes determining a plurality of positive cell percentages for a first cell feature for each field of view or for each patient based on a plurality of normalized expression cutoffs for all fields of view. The method further includes correlating positive cell percentages with assessments for each field of view or each patient. The method also includes identifying a combination of a cell feature for expression of a biomarker and a normalized expression cutoff that most closely correlate the positive cell percentage with the assessment.

Abstract: A stored data set comprises cell profile data including multiplexed biometric image data describing the expression of biomarkers. The data set includes an association of the cell profile data with a field of view level or a patient-level assessment. Cell features are calculated based on the cell's expression of each of the biomarkers. Moments of cell features are calculated from the data set, and combinations are examined for an association with an assessment. A predictive set of moments is selected based on the performance of the combination.

Abstract: Cell profile data is stored. The cell profile data comprises multiplexed biometric images capturing the expression of a plurality of biomarkers by at least one tissue sample from a patient with respect to at least one field of view. Individual cells are delineated and segmented into compartments. At least one cell feature is calculated based on the cell's expression of each of a plurality of biomarkers. A first moment is calculated for each cell feature. The moments are examined for an association with a diagnosis, a prognosis of a response to treatment of a condition or disease. Apparatus for performing the foregoing steps are disclosed.

Abstract: A data set of cell profile data is stored. The cell profile data includes multiplexed biometric image data describing the expression of a plurality of biomarkers. Cell profile data is generated from tissue samples drawn from a cohort of patients having an assessment related to the commonality. Multiple sets of clusters of similar cells are generated from the data set; the proportion of cells in each cluster is examined for an association with a diagnosis, a prognosis, or a response; and a predictive set of clusters is selected based on model performance. One predictive set of clusters is selected based on a comparison of the performance of at least one model of the plurality of sets of clusters. Display techniques that aid in understanding the characteristics of a cluster are disclosed.

Abstract: A data set of cell profile data is stored. The cell profile data includes multiplexed biometric image data describing the expression of a plurality of biomarkers with respect to a field of view in which individual cells are delineated and segmenting into compartments. Each cell in the field is assigned to a single cluster in a selected set of clusters based on cell similarity; cell similarity is determined based on a plurality of selected cell attributes. The proportion of cells in each cluster is observed. The observed proportions are examined for an association with a diagnosis, a prognosis, or a response derived from a known association of the selected set of clusters with at least one piece of meta-information including a field of view level assessment or a patient-level assessment.

Abstract: A method for motion compensation includes acquiring an initial volumetric localizer to establish an initial object position and initial object orientation at an initial state, acquiring a fast localizer of the object at a present state, aligning the fast localizer to the initial volumetric localizers to determine object motion between the initial state and the present state, and modifying an imaging protocol using the object position and orientation at the present state.

Abstract: Infrared radiation detection systems and methods of making the same are provided. In one embodiment, the radiation detection system comprises: a housing having an open end exposed to a radiation emitting object; a detector positioned in the housing, the detector comprising a radiation sensing material for detecting infrared radiation, the radiation sensing material having a portion removed by etching or coated by a mask such that only a region of the radiation sensing material is capable of detecting the infrared radiation; and a lens positioned in the housing for transmitting infrared radiation from the object to the detector.

Abstract: A fault tolerant synchronous permanent magnet machine is disclosed that reduces rotor losses by limiting eddy-current losses in the retaining sleeve. The machine limits eddy-current loss by any one or combination of axially segmenting the retaining sleeve, providing a highly electrically conductive non-magnetic shield to the retaining sleeve, and by configuring stator teeth width, stator teeth tip width, and slot distribution of the stator.

Abstract: A method and apparatus for depositing a coating material on a surface of a substrate by an ion plasma deposition process using a hollow cathode is disclosed. The cathode may be a substantially cylindrical hollow cathode. A plasma arc is formed on the outer circumference of the cathode to remove coating material from the cathode, which is then deposited on a surface of a substrate. An internal arc drive magnet is contained within the hollow bore of the cathode and cooling is provided to the magnet during operation.