Abstract: The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [18F]-labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [18F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for purifying two consecutive batches of a reaction mixture comprising an 18F-labelled compound.
Type:
Grant
Filed:
November 12, 2015
Date of Patent:
May 26, 2020
Assignee:
GE HEATLHCARE LIMITED
Inventors:
Xavier Franci, Steve Lignon, Audrey Marie Lange, Nicolas Verbrugge