Abstract: Pharmaceutical compositions and methods of using said pharmaceutical compositions are provided herein. A method of preventing preterm birth in a pregnant individual is also provided, said method comprising administering to said individual a pharmaceutical composition comprising a compound of Formula XX or a lactone thereof of formula XIX or XXI and preventing said preterm birth by said administration.
Type:
Grant
Filed:
February 2, 2023
Date of Patent:
February 18, 2025
Assignee:
Gedea Biotech AB
Inventors:
Ulf Ellervik, Olov Sterner, Helena Strevens, Sophie Manner
Abstract: The present invention relates to a pharmaceutical formulation for vaginal administration, wherein the formulation comprises a pharmaceutical acceptable excipient and glucono ?-lactone, wherein the glucono ?-lactone is present in an amount of 5 to 99 wt % of the formulation. The invention also relates to a pharmaceutical formulation according to the invention for use in the prevention or treatment of a urogenital fungal infection. Furthermore, the invention relates to glucono ?-lactone (formula (III)), for use in the in the prevention or treatment of a fungal infection.
Type:
Grant
Filed:
March 31, 2021
Date of Patent:
July 11, 2023
Assignee:
Gedea Biotech AB
Inventors:
Ulf Ellervik, Olov Sterner, Helena Strevens, Sophie Manner
Abstract: Pharmaceutical compositions and methods of using said pharmaceutical compositions are provided herein. A method of preventing preterm birth in a pregnant individual is also provided, said method comprising administering to said individual a pharmaceutical composition comprising a compound of Formula XX or a lactone thereof of formula XIX or XXI and preventing said preterm birth by said administration.
Type:
Application
Filed:
February 2, 2023
Publication date:
June 15, 2023
Applicant:
GEDEA BIOTECH AB
Inventors:
Ulf ELLERVIK, Olov STERNER, Helena STREVENS, Sophie MANNER
Abstract: The present invention concerns a pharmaceutical composition comprising a compound of Formula I for use in the treatment and/or prevention of microbial infections. Furthermore, the present invention concerns a method for prevention and/or reduction of biofilm formation.
Type:
Grant
Filed:
October 5, 2018
Date of Patent:
March 28, 2023
Assignee:
Gedea Biotech AB
Inventors:
Ulf Ellervik, Olov Sterner, Helena Strevens, Sophie Manner
Abstract: The present invention concerns a pharmaceutical composition comprising glucono-?-lactone, which is suitable for use in the treatment of vaginal microbial infections.
Type:
Application
Filed:
April 3, 2020
Publication date:
June 23, 2022
Applicant:
GEDEA BIOTECH AB
Inventors:
Ulf Ellervik, Sophie Manner, Olov Sterner, Helena Strevens, Nils-Olof Lindberg, Annette Säfholm
Abstract: The present invention relates to a pharmaceutical formulation for vaginal administration, wherein the formulation comprises a pharmaceutical acceptable excipient and glucono ?-lactone, wherein the glucono ?-lactone is present in an amount of 5 to 99 wt % of the formulation. The invention also relates to a pharmaceutical formulation according to the invention for use in the prevention or treatment of a urogenital fungal infection. Furthermore, the invention relates to glucono ?-lactone (formula (III)), for use in the in the prevention or treatment of a fungal infection.
Type:
Grant
Filed:
April 6, 2017
Date of Patent:
May 4, 2021
Assignee:
Gedea Biotech AB
Inventors:
Ulf Ellervik, Olov Sterner, Helena Strevens, Sophie Manner
Abstract: The present invention concerns a pharmaceutical composition comprising a compound of Formula I for use in the treatment and/or prevention of microbial infections. Furthermore, the present invention concerns a method for prevention and/or reduction of biofilm formation.
Type:
Application
Filed:
October 5, 2018
Publication date:
August 13, 2020
Applicant:
GEDEA BIOTECH AB
Inventors:
Ulf ELLERVIK, Olov STERNER, Helena STREVENS, Sophie MANNER