Abstract: This disclosure provides non-naturally occurring truncated elastin molecules. The non-naturally occurring truncated elastin may improve the firmness, elasticity, brightness, hydration, tactile texture, and/or visual texture of skin. The non-naturally occurring truncated elastin may reduce degradation of the extracellular matrix.
Abstract: Provided are modified Gram-negative bacteria having an increased periplasmic volume. Also provided are methods of expressing exogenous genes in the bacteria and targeting protein production to the periplasmic space.
Abstract: Provided herein are non-naturally occurring polypeptides comprising a sequence of a fragment of a collagen and recombinant cells containing heterologous nucleic acid sequences encoding the non-naturally occurring polypeptides. Further provided herein are animal-free methods of generating and purifying such non-naturally occurring polypeptides using microorganisms, preferably from bacterial cells.
Type:
Grant
Filed:
October 4, 2021
Date of Patent:
May 17, 2022
Assignee:
GELTOR, INC.
Inventors:
Nikolay Ouzounov, Jeffrey R. Mellin, Julia Co
Abstract: This disclosure provides non-naturally occurring collagen and elastin molecules. The non-naturally occurring collagens and elastins include truncated collagens, truncated elastins, as well as fusion proteins thereof. The non-naturally occurring collagen and elastin are useful in foods, cosmetics and many other products and uses.
Type:
Grant
Filed:
April 2, 2020
Date of Patent:
January 4, 2022
Assignee:
GELTOR, INC.
Inventors:
Nikolay Ouzounov, Alexander Lorestani, Monica Bhatia
Abstract: This disclosure provides non-naturally occurring collagen and elastin molecules. The non-naturally occurring collagens and elastins include truncated collagens, truncated elastins, as well as fusion proteins thereof. The non-naturally occurring collagen and elastin are useful in foods, cosmetics and many other products and uses.
Type:
Grant
Filed:
September 27, 2018
Date of Patent:
November 23, 2021
Assignee:
GELTOR, INC.
Inventors:
Nikolay Ouzounov, Alexander Lorestani, Monica Bhatia
Abstract: Provided herein are non-naturally occurring polypeptides comprising a sequence of a fragment of a collagen and recombinant cells containing heterologous nucleic acid sequences encoding the non-naturally occurring polypeptides. Further provided herein are animal-free methods of generating and purifying such non-naturally occurring polypeptides using microorganisms, preferably from bacterial cells.
Type:
Grant
Filed:
February 9, 2021
Date of Patent:
November 16, 2021
Assignee:
GELTOR, INC.
Inventors:
Nikolay Ouzounov, Jeffrey R. Mellin, Julia Co
Abstract: This disclosure provides non-naturally occurring truncated elastin molecules. The non-naturally occurring truncated elastin may improve the firmness, elasticity, brightness, hydration, tactile texture, and/or visual texture of skin. The non-naturally occurring truncated elastin may reduce degradation of the extracellular matrix.
Abstract: This disclosure provides non-naturally occurring collagen and elastin molecules. The non-naturally occurring collagens and elastins include truncated collagens, truncated elastins, as well as fusion proteins thereof. The non-naturally occurring collagen and elastin are useful in foods, cosmetics and many other products and uses.
Type:
Grant
Filed:
April 2, 2020
Date of Patent:
June 22, 2021
Assignee:
GELTOR, INC.
Inventors:
Nikolay Ouzounov, Alexander Lorestani, Monica Bhatia
Abstract: This disclosure provides non-naturally occurring collagen and elastin molecules. The non-naturally occurring collagens and elastins include truncated collagens, truncated elastins, as well as fusion proteins thereof. The non-naturally occurring collagen and elastin are useful in foods, cosmetics and many other products and uses.
Type:
Grant
Filed:
April 2, 2020
Date of Patent:
June 8, 2021
Assignee:
GELTOR, INC.
Inventors:
Nikolay Ouzounov, Alexander Lorestani, Monica Bhatia
Abstract: Provided are modified Gram-negative bacteria having an increased periplasmic volume. Also provided are methods of expressing exogenous genes in the bacteria and targeting protein production to the periplasmic space.
Abstract: This disclosure provides non-naturally occurring collagen and elastin molecules. The non-naturally occurring collagens and elastins include truncated collagens, truncated elastins, as well as fusion proteins thereof. The non-naturally occurring collagen and elastin are useful in foods, cosmetics and many other products and uses.
Type:
Application
Filed:
September 27, 2018
Publication date:
May 23, 2019
Applicants:
Geltor, Inc., Geltor, Inc.
Inventors:
Nikolay Ouzounov, Alexander Lorestani, Monica Bhatia