Abstract: A polycomplex comprising multiple Poly-lysine compounds, said Poly-lysine compounds being composed of at least one small molecule conjugated with a Poly-lysine. Compositions comprising the polycomplex and methods for treating an amyotrophic lateral sclerosis patient, the methods comprising administering to the patient one or more of the compositions.

Abstract: Disclosed is a method for identifying and characterizing compounds conjugating at least one polylysine and at least one other molecule chosen from the acids, fatty acids, vitamins, amino acids, amino acid derivatives having a neurotransmitter activity and the active substances having a therapeutic effect, the method including at least: a step of identification, by infrared spectroscopy, and at least one characterization step chosen from: ultraviolet-visible absorption spectroscopy, gas phase chromatography, high-performance liquid phase chromatography.

Abstract: A composition for controlling the progression of multiple sclerosis includes at least: One conjugate between poly-lysine and at least one fatty acid, and One conjugate between poly-lysine and at least one antioxidant, and One conjugate between poly-lysine and at least one amino acid derivative.

Abstract: The invention relates to the use of a composition for controlling the evolution of amyotrophic lateral sclerosis, characterised in that it comprises at least: a conjugate of poly-lysine and at least one anti-oxidant, and a conjugate of poly-lysine and at least one fatty acid. The invention also relates to a particular composition for controlling the evolution of amyotrophic lateral sclerosis.

Abstract: The invention relates to a method for detecting and supervising neurodegenerative diseases, which consists in detecting the presence of antibodies of the A-isotype and/or M-isotype which are directed against the antigens which are associated with these diseases. The invention also relates to a kit for the implementation of this method.