Patents Assigned to Gemma Biotechnology Ltd.
  • Induction of antibiotic proteins and peptides by LAIT/sCD14-protein
    Patent number: 7592310
    Abstract: A method of ameliorating the symptoms of sepsis comprising directly exposing epithelial cells of a mammal in need thereof to soluble CD14, or active variants thereof. A method of obtaining CD14 from a stock solution containing protein of a mammary secretion is described. A method of directly activating B cells using a soluble polypeptide having the amino acid sequence selected from the group consisting of leu-leu-leu-leu-leu-leu-pro-ser, leu-leu-leu-leu-leu-leu-pro-leu; and leu-leu-leu-leu-leu-leu-val-his, and which is specifically recognized by the monoclonal antibody 3C10 and which activates B cells is described. Bovine CD14 genomic DNA is described.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: September 22, 2009
    Assignee: Gemma Biotechnology Ltd.
    Inventors: Michael H. Julius, Dominik Filipp
  • Induction of antibiotic proteins and peptides by LAIT/sCD14-protein
    Publication number: 20040259795
    Abstract: A method of ameliorating the symptoms of sepsis comprising directly exposing epithelial cells of a mammal in need thereof to soluble CD14, or active variants thereof. A method of obtaining CD14 from a stock solution containing protein of a mammary secretion is described. A method of directly activating B cells using a soluble polypeptide having the amino acid sequence selected from the group consisting of leu-leu-leu-leu-leu-leu-pro-ser, leu-leu-leu-leu-leu-leu-pro-leu; and leu-leu-leu-leu-leu-leu-val-his, and which is specifically recognized by the monoclonal antibody 3C10 and which activates B cells is described. Bovine CD14 genomic DNA is described.
    Type: Application
    Filed: July 15, 2004
    Publication date: December 23, 2004
    Applicant: GEMMA BIOTECHNOLOGY LTD.
    Inventors: Michael H. Julius, Dominik Filipp