Patents Assigned to GENALYTE, INC.
  • METHODS AND COMPOSITIONS FOR POINT OF CARE MEASUREMENT OF THE BIOAVAILABILITY OF THERAPEUTIC BIOLOGICS
    Publication number: 20210231651
    Abstract: Embodiments provided herein relate to methods, compositions and systems for rapid determination of the bioavailability of a therapeutic biologic in a sample from a subject.
    Type: Application
    Filed: April 29, 2019
    Publication date: July 29, 2021
    Applicant: Genalyte, Inc.
    Inventors: David BROWN, Martin Anthony GLEESON
  • Biosensors based on optical probing and sensing
    Patent number: 11041811
    Abstract: Apparatus, sensor chips and techniques for optical sensing of substances by using optical sensors on sensor chips.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: June 22, 2021
    Assignee: GENALYTE, INC.
    Inventors: Lawrence Cary Gunn, III, Muzammil Iqbal, Brad Spaugh, Frank Tybor
  • Label-free optical sensors
    Patent number: 10365224
    Abstract: Techniques, apparatus and systems are described for performing label-free monitoring of processes. In one aspect, a label-free monitoring system includes an array of label-free optical sensors to detect an optical signal in response to synthesis of one or more target genetic structures. Each label-free optical sensor is functionalized with a respective target genetic structure. The system also includes a fluid flow control module that includes fluid receiving units to provide paths for different fluids to flow into the fluid flow control module and at least one switch connected to the fluid receiving units to selectively switch among the fluid receiving units to receive a select sequence of the fluids through the fluid receiving units. The select sequence of the fluids includes at least a dNTP or base.
    Type: Grant
    Filed: December 8, 2008
    Date of Patent: July 30, 2019
    Assignee: GENALYTE, INC.
    Inventor: Lawrence Cary Gunn, III
  • Optical analyte detection systems and methods of use
    Patent number: 9921165
    Abstract: Various embodiments are drawn to systems and methods for detecting an analyte of interest in a sample including an optical sensor, a capture probe attached to a surface of the optical sensor wherein the capture probe is capable of binding to the analyte to form a duplex or complex, and an antibody capable of binding to the analyte, duplex, or complex. In several embodiments, systems and methods further include a particle attached to the antibody or capable of binding to the antibody. In several embodiments, systems and methods for analyte detection feature one or more of the following: high detection sensitivity and specificity, scalability and multiplex capacity, ability to analyze large analytes, and ability to detect or measure multiple individual binding events in real-time.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: March 20, 2018
    Assignees: Genalyte, Inc., The Board of Trustees of the University of Illinois
    Inventors: Ryan C. Bailey, Abraham J. Qavi, Jared T. Kindt, Ji-Yeon Byeon, Matthew S. Luchansky, Melinda S. McClellan, Adam L. Washburn, Tate Owen, Martin Anthony Gleeson, Lawrence C. Gunn, III
  • Biosensors based on optical probing and sensing
    Patent number: 9846126
    Abstract: Apparatus, sensor chips and techniques for optical sensing of substances by using optical sensors on sensor chips.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: December 19, 2017
    Assignee: Genalyte, Inc.
    Inventors: Lawrence Cary Gunn, III, Muzammil Iqbal, Brad Spaugh, Frank Tybor
  • BIOSENSORS BASED ON OPTICAL PROBING AND SENSING
    Publication number: 20120092650
    Abstract: Apparatus, sensor chips and techniques for optical sensing of substances by using optical sensors on sensor chips.
    Type: Application
    Filed: October 27, 2009
    Publication date: April 19, 2012
    Applicant: GENALYTE, INC.
    Inventors: Lawrence Cary Gunn, III, Muzummil Iqbal