Abstract: Complete nucleic acid library preparation devices are provided. Aspects of the devices include: a thermal chip module comprising multiple nodes; one or more plate locations; a robotically controlled liquid handler configured to transfer liquid between the one or more plate locations and the thermal chip module; and a bulk reagent dispenser configured to access each node of the thermal chip module.
Abstract: Aspects of the present disclosure include a complete genomic analysis device and methods of use thereof for high throughput genomic analysis of biological samples.
Type:
Grant
Filed:
August 3, 2015
Date of Patent:
April 23, 2019
Assignee:
GENCELL BIOSYSTEMS LTD.
Inventors:
Mark Dalton, John Daly, Mark McCabe, Padraig Walsh, Kevin Daulnay, David McGuire, Maria Kerin, Maria O'Connor, Colin King, Keith Mooney
Abstract: Complete nucleic acid library preparation devices are provided. Aspects of the devices include: a thermal chip module comprising multiple CLC reaction wells; one or more plate locations; a robotically controlled liquid handler configured to transfer liquid between the one or more plate locations and the thermal chip module; and a bulk reagent dispenser configured to access each CLC reaction well of the thermal chip module.
Type:
Grant
Filed:
August 3, 2015
Date of Patent:
February 19, 2019
Assignee:
GENCELL BIOSYSTEMS LTD.
Inventors:
Brian Barrett, Noel Sirr, Brian Chawke, Kieran Curran, John Daly
Abstract: A sample handling method may include drawing an encapsulating liquid from an encapsulating-liquid input; discharging the drawn encapsulating liquid (a) onto a free surface of a carrier liquid in a carrier-liquid conduit comprising a stabilisation feature and (b) proximate to the stabilisation feature, the encapsulating liquid being immiscible with the carrier liquid, so that the discharged encapsulating liquid does not mix with the carrier liquid, floats on top of the carrier liquid, and is immobilised by the stabilisation feature; drawing a sample liquid from a sample-liquid input; and discharging the drawn sample liquid, the sample liquid being immiscible with the encapsulating liquid and with the carrier liquid, so that the sample liquid does not mix with the encapsulating liquid or with the carrier liquid.
Type:
Application
Filed:
July 22, 2011
Publication date:
February 23, 2012
Applicant:
GENCELL BIOSYSTEMS LTD.
Inventors:
Kieran Curran, Paul Fleming, Séamus Gillhooley, Micheál Keane, Inga Rosca, Patrick Tuohy