Abstract: Methods of treating and/or preventing disorders mediated by one or more of TNF-?, NF-?B, IKK-?, IKK-?, ATF-2 and p38 kinase by administration of praziquantel, or a pharmaceutically acceptable salt, prodrug, ester or amide thereof. These disorders include inflammatory disorders such as autoimmune diseases.
Type:
Application
Filed:
May 19, 2008
Publication date:
December 4, 2008
Applicant:
Gencross, Inc.
Inventors:
Deug Yong Shin, Tae Saeng Choi, Dong Hoon Jin, Min Kyung Cho
Abstract: Methods of treating and/or preventing disorders mediated by one or more of TNF-?, NF-?B, IKK-?, IKK-?, ATF-2 and p38 kinase by administration of praziquantel, or a pharmaceutically acceptable salt, prodrug, ester or amide thereof. These disorders include inflammatory disorders such as autoimmune diseases.