Patents Assigned to Gene Stream Pty Limited
  • Mouse for predicting a behavior of drugs in humans
    Patent number: 9497944
    Abstract: The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes, such as serum albumin, or portions of genes have been replaced by homologs from another animal, such as a human, to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: November 22, 2016
    Assignee: GENE STREAM PTY LIMITED
    Inventor: John Michael Daly
  • MOUSE FOR PREDICTING A BEHAVIOR OF DRUGS IN HUMANS
    Publication number: 20140096273
    Abstract: The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes, such as serum albumin, or portions of genes have been replaced by homologs from another animal, such as a human, to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
    Type: Application
    Filed: August 30, 2013
    Publication date: April 3, 2014
    Applicant: GENE STREAM PTY LIMITED
    Inventor: John Michael Daly
  • Method of predicting a behavior of one or more drugs
    Patent number: 8524975
    Abstract: The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: September 3, 2013
    Assignee: Gene Stream Pty Limited
    Inventor: John Michael Daly
  • METHOD OF PREDICTING A BEHAVIOR OF ONE OR MORE DRUGS
    Publication number: 20120167236
    Abstract: The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
    Type: Application
    Filed: March 9, 2012
    Publication date: June 28, 2012
    Applicant: GENE STREAM PTY LIMITED
    Inventor: John Michael Daly
  • Transgenic non-human animals for pharmacological and toxicological studies
    Patent number: 8148599
    Abstract: The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: April 3, 2012
    Assignee: Gene Stream Pty Limited
    Inventor: John Michael Daly
  • TRANSGENIC NON-HUMAN ANIMALS FOR PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES
    Publication number: 20100319076
    Abstract: The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 16, 2010
    Applicant: GENE STREAM PTY LIMITED
    Inventor: John Michael Daly
  • Transgenic non-human animals for pharmacological and toxicological studies
    Patent number: 7781643
    Abstract: The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
    Type: Grant
    Filed: April 13, 2009
    Date of Patent: August 24, 2010
    Assignee: Gene Stream Pty Limited
    Inventor: John Michael Daly
  • TRANSGENIC NON-HUMAN ANIMALS FOR PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES
    Publication number: 20090241204
    Abstract: The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
    Type: Application
    Filed: April 13, 2009
    Publication date: September 24, 2009
    Applicant: GENE STREAM PTY LIMITED
    Inventor: JOHN MICHAEL DALY
  • Transgenic non-human animals for pharmacological and toxicological studies
    Patent number: 7544854
    Abstract: The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: June 9, 2009
    Assignee: Gene Stream Pty Limited
    Inventor: John Michael Daly