Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders.
Type:
Grant
Filed:
May 10, 2001
Date of Patent:
October 3, 2006
Assignee:
Genentch, Inc.
Inventors:
Jian Chen, Ellen Filvaroff, Audrey Goddard, Austin Gurney, Hanzhong Li, William I. Wood
Abstract: Compositions and methods for improving detection sensitivity in nucleic acid microarray analysis are disclosed, including methods of purifying nucleic acids, methods of synthesizing fluorescent DNA probes, methods of hybridization, and methods of activating a substrate for target molecule attachment are disclosed.
Type:
Application
Filed:
September 10, 2003
Publication date:
September 7, 2006
Applicant:
Genentch, Inc.
Inventors:
Sarah Bodary, Hilary Clark, Brisdell Hunte, Janet Jackman, Jill Schoenfeld, P. Williams, William Wood, Thomas Wu