Abstract: The present invention relates to a method for display of proteinson spore surface and a method for improving protein with rapidity using the same, which comprises the steps of (i) preparing a vector for spore surface display comprising a gene construct containing a gene encoding spore coat protein and a gene encoding a protein of interest, wherein, when expressed, the gene construct expresses a fusion protein between the spore coat protein and the protein of interest, (ii) transforming a host cell with the vector for spore surface display; (iii) displaying the protein of interest on a surface of a spore of the host cell; and (iv) recovering the spore displaying on its surface the protein of interest.
Type:
Grant
Filed:
December 7, 2001
Date of Patent:
September 1, 2009
Assignee:
Geneofocus Co., Ltd.
Inventors:
June-Hyung Kim, Byung-Gee Kim, Soo-Keun Choi, Heung-Chae Jung, Jae-gu Pan