Abstract: Provided herein are materials and methods for detecting colorectal neoplasms and colon cancer based on the expression levels of stool-derived eukaryotic RNA biomarkers in eukaryotic nucleic acid present in a stool sample from a subject, for example, a patient. The methods can be used for the detection of high-risk adenomas and colorectal neoplasm molecular subtypes.
Type:
Grant
Filed:
January 19, 2022
Date of Patent:
October 25, 2022
Assignee:
GENEOSCOPY, INC.
Inventors:
Andrew Barnell, Erica Barnell, Yiming Kang, Elizabeth Wurtzler, Katie Campbell
Abstract: Provided herein are materials and methods for isolation of eukaryotic nucleic acid from a human or non-human animal stool sample. Also provided are methods of analysis of eukaryotic biomarkers present in a human or non-human animal stool sample.
Type:
Grant
Filed:
October 27, 2017
Date of Patent:
October 25, 2022
Assignee:
GENEOSCOPY, INC.
Inventors:
Erica Barnell, Andrew Barnell, Yiming Kang, Elizabeth Wurtzler