Patents Assigned to Genera Istrazivanja d.o.o.
  • BMP-1 Procollagen C-Proteinase for Diagnosis and Treatment of Bone and Soft Tissue Defects and Disorders
    Publication number: 20140356378
    Abstract: Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.
    Type: Application
    Filed: June 2, 2014
    Publication date: December 4, 2014
    Applicant: GENERA ISTRAZIVANJA d.o.o
    Inventors: Slobodan VUKICEVIC, Lovorka GRGUREVIC, Boris MACEK
  • Methods and compositions for regenerating articular cartilage
    Patent number: 8796208
    Abstract: Methods and compositions are described to regenerate cartilage in a partial thickness defect or area of reduced volume of articular cartilage comprising an infiltration suppressor agent and a columnar growth promoting agent.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: August 5, 2014
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Slobodan Vukicevic, Mislav Jelic
  • Methods of preventing ischemia/reperfusion damage to kidney using antibodies that bind BMP-1 isoforms
    Patent number: 8765127
    Abstract: Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: July 1, 2014
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Slobodan Vukicevic, Lovorka Grgurevic, Boris Macek
  • BMP-1 Procollagen C-Proteinase for Diagnosis and Treatment of Bone and Soft Tissue Defects and Disorders
    Publication number: 20130171156
    Abstract: Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.
    Type: Application
    Filed: February 28, 2013
    Publication date: July 4, 2013
    Applicant: GENERA ISTRAZIVANJA D.O.O.
    Inventor: Genera Istrazivanja D.O.O.
  • ADAMTS4 as a blood biomarker and therapeutic target for chronic renal failure
    Patent number: 8263072
    Abstract: ADAMTS4 is found to be useful as a blood biomarker for chronic renal failure and also as a therapeutic target for treating chronic renal failure in a human individual. A change in the level of expression of selected genes as disclosed herein in kidney tissue of an individual may also be used to diagnose chronic renal failure in an individual.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: September 11, 2012
    Assignee: Genera Istrazivanja, d.o.o.
    Inventors: Lovorka Grgurevic, Slobodan Vukicevic
  • Methods and Compositions for Regenerating Articular Cartilage
    Publication number: 20120149641
    Abstract: Methods and compositions are described to regenerate cartilage in a partial thickness defect or area of reduced volume of articular cartilage comprising an infiltration suppressor agent and a columnar growth promoting agent.
    Type: Application
    Filed: February 21, 2012
    Publication date: June 14, 2012
    Applicant: GENERA ISTRAZIVANJA d.o.o.
    Inventors: Slobodan VUKICEVIC, Mislav JELIC
  • Whole blood-derived coagulum device for treating bone defects
    Patent number: 8197840
    Abstract: Whole blood-derived coagulum devices are described for use in treating bone defects.
    Type: Grant
    Filed: July 23, 2007
    Date of Patent: June 12, 2012
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Slobodan Vukicevic, Lovorka Grgurevic, Hermann Oppermann
  • Blood biomarkers for bone fracture and cartilage injury
    Patent number: 8182998
    Abstract: Blood biomarkers are described for use in methods and compositions to determine whether an individual has sustained a bone fracture or a cartilage injury.
    Type: Grant
    Filed: April 28, 2008
    Date of Patent: May 22, 2012
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Lovorka Grgurevic, Boris Macek, Slobodan Vukicevic
  • Methods and compositions for regenerating articular cartilage
    Patent number: 8119591
    Abstract: Methods and compositions are described to regenerate cartilage in a partial thickness defect or area of reduced volume of articular cartilage comprising an infiltration suppressor agent and a columnar growth promoting agent.
    Type: Grant
    Filed: August 1, 2006
    Date of Patent: February 21, 2012
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Slobodan Vukicevic, Mislav Jelic
  • BMP-1 PROCOLLAGEN C-PROTEINASE FOR DIAGNOSIS AND TREATMENT OF BONE AND SOFT TISSUE DEFECTS AND DISORDERS
    Publication number: 20110076281
    Abstract: Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.
    Type: Application
    Filed: December 9, 2010
    Publication date: March 31, 2011
    Applicant: GENERA ISTRAZIVANJA d.o.o
    Inventors: Slobodan Vukicevic, Lovorka Grgurevic, Boris Macek
  • Control of Exocrine Pancreatic Function Using Bone Morphogenetic Proteins
    Publication number: 20110047633
    Abstract: Methods are described for controlling exocrine pancreatic function, for reducing the level of amylase in the blood, and for treating pancreatitis in an individual comprising administering to the individual a bone morphogenetic protein (BMP). Methods for identifying candidate molecules for use in treating diabetes are also described.
    Type: Application
    Filed: September 8, 2010
    Publication date: February 24, 2011
    Applicant: GENERA ISTRAZIVANJA D.O.O.
    Inventors: Slobodan VUKICEVIC, Petra SIMIC
  • BMP-1 procollagen c-proteinase for diagnosis and treatment of bone and soft tissue defects and disorders
    Patent number: 7850964
    Abstract: Uses of BMP-1 isoforms for diagnosing and treating defects and disorders of bone and soft tissues are described. Also described is a newly isolated variant of the BMP-1 isoform BMP-1-3.
    Type: Grant
    Filed: July 23, 2007
    Date of Patent: December 14, 2010
    Assignee: Genera Istrazivanja d.o.o.
    Inventors: Slobodan Vukicevic, Lovorka Grgurevic, Boris Macek
  • ADAMTS4 as a blood biomarker and therapeutic target for chronic renal failure
    Publication number: 20100254997
    Abstract: ADAMTS4 is found to be useful as a blood biomarker for chronic renal failure and also as a therapeutic target for treating chronic renal failure in a human individual. A change in the level of expression of selected genes as disclosed herein in kidney tissue of an individual may also be used to diagnose chronic renal failure in an individual.
    Type: Application
    Filed: June 20, 2008
    Publication date: October 7, 2010
    Applicant: GENERA ISTRAZIVANJA D.O.O.
    Inventors: Lovorka Grgurevic, Slobodan Vukicevic