Abstract: Methods and systems are provided to form a single coherent beam of light from a plurality of smaller beams of light. In one implementation a beam combiner comprising a beam director is configured to direct a seed beam of coherent light and a plurality of pump beams of coherent light; and a nonlinear converter is configured to combine the seed beam and the plurality of pump beams directed by the beam director to produce a substantially coherent wave front.

Abstract: An apparatus and method for selectively dissociating target molecular species present in a gas mixture is disclosed. An embodiment of an apparatus of the present invention comprises a containment structure for containing a gas mixture having a target molecular species; and a radiation source proximate to the containment structure and configured to apply electromagnetic energy to the gas mixture in the containment structure, the electromagnetic energy having a wavelength that dissociates molecules of the target species. An embodiment of a method of the present invention comprises the steps of containing a gas mixture having a heavy hydrocarbon; and applying to the gas mixture electromagnetic energy having a wavelength that dissociates molecules of the heavy hydrocarbon.

Abstract: A persistent archive of a collection of data objects comprises a self-describing, infrastructure-independent representation of a logical structure for the collection and a self-describing, infrastructure-independent representation of the data objects. The archive is persistent in that it may be instantiated at an indefinite point in time in the future regardless of the state of technology at that time. A knowledge-based persistent archive of a collection of data objects comprises the foregoing two elements but also a self-describing, infrastructure-independent representation of knowledge relevant to the collection.

Abstract: The present invention provides compositions and methods for reversibly inhibiting S-adenosyl-L-homocysteine (SAH) hydrolase. The compounds of the present invention can be used as an anti-hemorrhagic viral infection agent, an immunosuppressant, a homocysteine lowering agent, or an anti-neoplasm agent. The compositions and methods of the present invention can be used for the prevention and treatment of hemorrhagic virus infection, autoimmune diseases, autograft rejection, neoplasm, hyperhomocysteineuria, cardiovascular disease, stroke, Alzheimer's disease, multiple sclerosis or diabetes.

Abstract: Capacitor based pulse forming networks and methods are provided which require fewer inductors are that pulsed more frequently to provide a smaller, lower mass, and lower inductance pulse forming network having better pulse shaping characteristics than conventional pulse forming networks. In one implementation, the invention can be characterized as a capacitor based pulse forming network comprising a plurality of inductors adapted to be coupled to a load, a plurality of capacitor units, and a plurality of switches. Each switch couples a respective capacitor unit to a respective inductor, wherein multiple capacitor units are coupled to each inductor by separate switches. The plurality of switches are adapted to non-simultaneously discharge at least some of the multiple capacitor units to provide non-simultaneous pulses through a given inductor to the load and not through other inductors. The non-simultaneous pulses form at least a portion of an output pulse waveform to the load.

Abstract: A gun barrel for firing a projectile and particularly a rail gun barrel that comprises a pair of spaced apart rails and a pair of spaced apart insulators, which separate the rails, and together define a composite bore, all disposed centrally within an outer rigid tube. A prestressed filament-wound polymeric resin shell immediately surrounds and applies compressive stress to this composite, bore-defining structure. A pressure medium, positioned between the shell and the interior surface of the outer tube, is operative to apply compressive stress to the shell at least at locations generally radially outward of the rails. The compressive stresses applied by the combination of the prestressed shell and the pressure medium are additive and effectively preload the rails and the composite bore structure to resist overall forces encountered during projectile firing which, in a rail gun, include asymmetric loads upon the rails from electromagnetic repulsion forces and also axisymmetric bursting forces.

Abstract: A system for testing radar in accordance with one embodiment comprising a target motion platform; a target motion platform controller for controlling motion of the platform; a radar responsive tag and a delay line located on the target motion platform; the radar which is being tested; and a motion measurement simulator for inputting data to the radar electronics assembly to simulate movement of the radar. In some embodiments the system further comprises a radar motion platform, wherein the radar electronics assembly is positioned on the radar motion platform; a radar motion platform controller for controlling the movement of the radar motion platform; and a master controller coupled to the radar motion platform controller and the target motion platform controller.

Abstract: Alkali-vapor laser and related methods of lasing are described herein. In some embodiments, a diode-pumped gas-vapor laser is provided that can be scaled to high power. For example, in one embodiment, a triply-transverse configuration of a diode-pumped-alkali-laser (DPAL) is disclosed in which alkali-buffer gain medium is flowed through an laser chamber (for example, configured as an optical resonator or amplifier) whose optical axis is nominally transverse to the flow direction, and whose pump array radiation is propagated into the alkali-buffer gain medium in a direction nominally transverse to both the direction of gain medium flow and the direction of the optical axis.

Abstract: This invention relates generally to the field of homocysteine detection. In particular, the invention provides a method for determining homocysteine presence or concentration in samples, which method comprises: contacting a sample containing or suspected of containing Hcy with a Hcy co-substrate and a Hcy converting enzyme in a Hcy conversion reaction to form a Hcy conversion product and a Hcy co-substrate conversion product; and assessing the Hcy co-substrate conversion product to determine the presence, absence and/or amount of the Hcy in the sample. The Hcy co-substrate conversion product may be assessed directly, or it may be assessed by further conversion of the Hcy co-substrate conversion product into another material by the action of one or more additional enzymes. A kit for assaying homocysteine based on the same principle is also provided.

Abstract: A system for generating an electrical current in a circuit includes a rotor, a stator and a motor for rotating the rotor about a rotation axis. A plurality of permanent magnets are mounted on the rotor and radially distanced from the rotation axis. With this structure, the permanent magnets rotate with the rotor to establish a time-varying magnetic field. A winding is attached to the stator, connected to the circuit and immersed in the time-varying magnetic field generated by the permanent magnets. In one implementation, a switch is provided to reconfigure the circuit between a first, open-circuit configuration in which little or no current flows through the circuit, and a second closed-circuit configuration in which a current is generated at the winding for flow through the circuit.

Abstract: A method of data transmission according to one embodiment of the invention includes transmitting a plurality of bursts to transmit data, each burst occupying at least one of a plurality of frequency bands. Specifically, a bandwidth of at least one of the plurality of bursts is at least two percent of the center frequency of the burst. In one preferred embodiment, a bandwidth of at least one of the plurality of bursts is at least 100 MHz. In another preferred embodiment, each burst occupies at least one of the plurality of frequency bands, but less than all of the plurality of frequency bands.

Abstract: A method and apparatus for operation in a multi-frequency band wideband system in the presence of an interference, the method comprising the steps: receiving signaling in a plurality of wideband frequency sub-bands, each wideband frequency sub-band having a different center frequency, wherein a bandwidth of each wideband frequency sub-band is at least 2 percent of a center frequency of the wideband frequency sub-band; detecting an interfering signal having signal energy in a portion of a respective sub-band of the wideband frequency sub-bands; modifying at least one of a center frequency and a bandwidth of the respective sub-band in order to operate in the presence of the interfering signal; and instructing a transmitting device transmitting the signaling to transmit subsequent signaling accounting for the modification of the center frequency of the respective sub-band.

Abstract: A magnetic test apparatus, in accordance with one embodiment, comprising a rotor coupled to a drive shaft, wherein the drive shaft is mechanically coupled to a drive system; a stator coupled to at least one brush holder; at least one brush held by the brush holder, wherein the brush is held in contact with the rotor; a housing for supporting the rotor and the stator; and a magnet for providing a magnetic field in the vicinity of the at least one brush.

Abstract: The present invention relates to methods for assaying inhibitors for S-adenosylhomocysteine (SAH) hydrolases and assaying inhibitors for S-adenosylmethionine (SAM)-dependent methyltransferases. The methods are amenable for use in high throughput formats. Kits for performing the methods are also provided.

Abstract: A method of data transmission according to one embodiment of the invention includes encoding a set of data values to produce a corresponding series of ordered n-tuples. The method also includes transmitting, according to the series of ordered n-tuples, a plurality of bursts over a plurality n of frequency bands. Specifically, for each of the plurality of bursts, a frequency band occupied by the burst is indicated by the order within its n-tuple of an element corresponding to the burst. A bandwidth of at least one of the plurality of bursts is at least two percent of the center frequency of the burst. Information is encoded into a polarity of at least one of the plurality of bursts.

Abstract: The present invention provides a method for assaying alpha-methylacyl-CoA racemase activity. In the assay, a sample containing an alpha-methylacyl-CoA racemase or suspected of containing an alpha-methylacyl-CoA racemase is contacted with (2R)-2-methylacyl-CoA. If alpha-methylacyl-CoA racemase is present in the sample, (2R)-2-methylacyl-CoA is converted into (2S)-2-methylacyl-CoA. The method then utilizes a cycling reaction system between (2S)-2-methylacyl-CoA and trans-2,3-dehydroacyl-CoA to generate a detectable signal that corresponds to the alpha-methylacyl-CoA racemase activity. Kits for assaying alpha-methylacyl-CoA racemase based on the same principle are also provided.

Abstract: The present invention provides a method for assaying alpha-methylacyl-CoA racemase activity. In the assay, a sample containing an alpha-methylacyl-CoA racemase or suspected of containing an alpha-methylacyl-CoA racemase is contacted with (2R)-pristanoyl-CoA. If alpha-methylacyl-CoA racemase is present in the sample, (2R)-pristanoyl-CoA is converted into (2S)-pristanoyl-CoA. The method then utilizes a cycling reaction system between (2S)-pristanoyl-CoA and trans-2,3-dehydropristanoyl-CoA to generate a detectable signal that corresponds to the alpha-methylacyl-CoA racemase activity. Kits for assaying alpha-methylacyl-CoA racemase based on the same principle are also provided.

Abstract: The invention relates generally to the field of potassium ion detection. In particular, the invention provides kits for assaying for potassium ions in a sample using a potassium-dependent urea amidolyase (UAL) enzyme.

Abstract: A system for testing radar in accordance with one embodiment comprising a target motion platform; a target motion platform controller for controlling motion of the platform; a radar responsive tag and a delay line located on the target motion platform; the radar which is being tested; and a motion measurement simulator for inputting data to the radar electronics assembly to simulate movement of the radar. In some embodiments the system further comprises a radar motion platform, wherein the radar electronics assembly is positioned on the radar motion platform; a radar motion platform controller for controlling the movement of the radar motion platform; and a master controller coupled to the radar motion platform controller and the target motion platform controller.

Abstract: A laser device which may be used as an oscillator or amplifier comprising a chamber having a volume formed therein and a gain medium within the volume. The gain medium comprises a solid-state element containing active laser ion within the volume. A cooling fluid flows about the solid-state element and a semiconductor laser diode provides optical pump radiation into the volume of the laser chamber such that laser emission from the device passes through the gain medium and the fluid. The laser device provides the advantages of a solid-state gain medium laser (e.g., diode-pumping, high power density, etc), but enables operation at higher average power and beam quality than would be achievable from a pure solid-state medium.