Patents Assigned to General Incorporated Association The Japan-Multinational Trial Organization
  • Publication number: 20230391860
    Abstract: The present disclosure relates to a neutralizing antibody specific to human denatured CRP that can be used for a medicine such as an anti-inflammatory agent. The present disclosure also relates to various inventions relating to the neutralizing antibody specific to human denatured CRP.
    Type: Application
    Filed: August 11, 2023
    Publication date: December 7, 2023
    Applicants: CANON MEDICAL SYSTEMS CORPORATION, General Incorporated Association The Japan-Multinational Trial Organization
    Inventors: Masaaki FUJITA, Cheng-long HUANG, Hiromi WADA, Yuki YASUDA, Yasuo SAKURAI
  • Publication number: 20230384326
    Abstract: The present disclosure relates to a method useful in the determination of adult Still's disease (ASD). More specifically, the present disclosure relates to (I) a method for testing adult Still's disease, including (1) measuring a denatured CRP concentration in a blood sample collected from a subject; and (2) comparing the measured denatured CRP concentration and/or an index value based on the denatured CRP concentration with a reference value; (II) a denatured CRP-specific antibody; and (III) a kit for testing adult Still's disease.
    Type: Application
    Filed: August 11, 2023
    Publication date: November 30, 2023
    Applicants: CANON MEDICAL SYSTEMS CORPORATION, General Incorporated Association The Japan-Multinational Trial Organization
    Inventors: Masaaki FUJITA, Cheng-long HUANG, Hiromi WADA, Yuki YASUDA, Yasuo SAKURAI
  • Patent number: 11534119
    Abstract: An analysis apparatus according to an embodiment includes an extraction unit, a calculation unit, and an evaluation unit. The extraction unit extracts a detection value in a tumor region, a blood region, and a muscle region from a nuclear medicine image of a subject administered with a drug containing a radiolabeled anticancer drug that works by accumulating in a tumor. The calculation unit calculates a first comparison value that is a comparison result between the detection value in the blood region and the detection value in the tumor region, and a second comparison value that is a comparison result between the detection value in the muscle region and the detection value in the tumor region. The evaluation unit evaluates an accumulation of the drug in the tumor, based on the first comparison value and the second comparison value calculated by the calculation unit.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: December 27, 2022
    Assignees: CANON MEDICAL SYSTEMS CORPORATION, National Institutes for Quantum Science and Technology, General Incorporated Association The Japan-Multinational Trial Organization
    Inventors: Shunsuke Fujiwara, Yasuo Sakurai, Ming-Rong Zhang, Lin Xie, Masayuki Fujinaga, Masayuki Hanyu, Cheng-Long Huang, Masakazu Fukushima, Hiromi Wada
  • Publication number: 20210128089
    Abstract: An analysis apparatus according to an embodiment includes an extraction unit, a calculation unit, and an evaluation unit. The extraction unit extracts a detection value in a tumor region, a blood region, and a muscle region from a nuclear medicine image of a subject administered with a drug containing a radiolabeled anticancer drug that works by accumulating in a tumor. The calculation unit calculates a first comparison value that is a comparison result between the detection value in the blood region and the detection value in the tumor region, and a second comparison value that is a comparison result between the detection value in the muscle region and the detection value in the tumor region. The evaluation unit evaluates an accumulation of the drug in the tumor, based on the first comparison value and the second comparison value calculated by the calculation unit.
    Type: Application
    Filed: October 27, 2020
    Publication date: May 6, 2021
    Applicants: CANON MEDICAL SYSTEMS CORPORATION, National Institutes for Quantum and Radiological Science and Technology, General Incorporated Association The Japan-Multinational Trial Organization
    Inventors: Shunsuke FUJIWARA, Yasuo SAKURAI, Ming-Rong ZHANG, Lin XIE, Masayuki FUJINAGA, Masayuki HANYU, Cheng-Long HUANG, Masakazu FUKUSHIMA, Hiromi WADA