Patents Assigned to General of Agency of Industrial Science
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Patent number: 7282481Abstract: A heparin-binding protein functionalized by covalently bonding thereto a sugar chain, a method for producing the protein and a pharmaceutical composition containing the protein as an active ingredient, as well as a method of functionalizing a natural protein having no sugar chain by covalently bonding thereto a sugar chain.Type: GrantFiled: November 23, 2005Date of Patent: October 16, 2007Assignee: Director-General of Agency of Industrial Science and TechnologyInventors: Toru Imamura, Masahiro Asada, Syuichi Oka, Masashi Suzuki, Atsuko Yoneda, Keiko Ota, Yuko Oda, Kazuko Miyakawa, Noriko Orikasa, Chie Asada, Tetsuhito Kojima
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Publication number: 20060079451Abstract: A heparin-binding protein functionalized by covalently bonding thereto a sugar chain, a method for producing the protein and a pharmaceutical composition containing the protein as an active ingredient, as well as a method of functionalizing a natural protein having no sugar chain by covalently bonding thereto a sugar chain.Type: ApplicationFiled: November 23, 2005Publication date: April 13, 2006Applicant: Director-General of Agency of Industrial Science and TechnologyInventors: Toru Imamura, Masahiro Asada, Syuichi Oka, Masashi Suzuki, Atsuko Yoneda, Keiko Ota, Yuko Oda, Kazuko Miyakawa, Noriko Orikasa, Chie Asada, Tetsuhito Kojima
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Patent number: 7005415Abstract: A heparin-binding protein functionalized by covalently bonding thereto a sugar chain, a method for producing the protein and a pharmaceutical composition containing the protein as an active ingredient, as well as a method for functionalizing a natural protein having no sugar chain by covalently bonding thereto a sugar chain.Type: GrantFiled: July 22, 1998Date of Patent: February 28, 2006Assignee: Director-General Agency of Industrial Science and TechnologyInventors: Toru Imamura, Masahiro Asada, Syuichi Oka, Masashi Suzuki, Atsuko Yoneda, Keiko Ota, Yuko Oda, Kazuko Miyakawa, Noriko Orikasa, Chie Asada, Tetsuhito Kojima
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Patent number: 6960454Abstract: The invention relates to a thermophilic enzyme having ?-glycosidase activity which comprises the amino acid sequence of SEQ ID NO: 2 in which one or a plurality of amino acid residues may be deleted, replaced or added.Type: GrantFiled: August 6, 1999Date of Patent: November 1, 2005Assignee: Director-General of Agency of Industrial Science and TechnologyInventors: Ikuo Matsui, Kazuhiko Ishikawa, Hiroyasu Ishida, Yoshitsugu Kosugi
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Patent number: 6787617Abstract: A process for preparing olefinic living polymers having a molecular weight distribution (Mw/Mn) of 1 to 1.3, comprising polymerizing an olefinic monomer having 2 to 20 carbon atoms at low temperatures in the presence of a catalyst comprising (A) a hafnium or zirconium-containing compound having one or two cyclopentadienyl backbones, (B) a triphenyl boron compound or a tetraphenyl borate compound and optionally (C) a specific mono-, di- or trialkylaluminum compound. When the catalyst comprising the zirconium-containing compound is prepared by further using a titanium-containing compound (D), the polymerization temperature can be raised.Type: GrantFiled: November 8, 2001Date of Patent: September 7, 2004Assignees: Japan as represented by Director General of the Agency of Industrial Science and Technology, Japan Chemical Innovation InstituteInventors: Kazuo Soga, Takeshi Shiono, Michihiko Asai, Yasuzo Suzuki, Akira Miyazawa, Kenji Tsuchihara, Masahide Murata, Hiroyuki Ozaki, Masanao Kawabe, Toshio Kase, Jizhu Jin, Hideaki Hagiwara, Yoshifumi Fukui
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Patent number: 6653430Abstract: A butadiene polymer (i) having a cis bond unit content of at least 50% based on the total butadiene units, a number average molecular weight (Mn) of 1,000 to 10,000,000, and at least 80%, based on the total molecular chains, of living chains containing a transition metal of group IV of the Periodic table at a terminal thereof; a polymer (ii) obtained by modifying terminals of the polymer (i); and a polymer (iii) obtained by coupling the polymers (i). These polymers (i), (ii) and (iii) are obtained by polymerizing a conjugated diene monomer alone or with a copolymerizable monomer at a specific temperature in the presence of a catalyst comprising a compound (A) of a transition metal of group IV of the periodic table having a cyclopentadienyl structure and a co-catalyst (B) selected from organoaluminum-oxy compound (a) and others and optionally further by contacting the resultant polymer with a terminal modifier or a coupling agent.Type: GrantFiled: June 18, 2001Date of Patent: November 25, 2003Assignees: Japan as Represented by Director General of the Agency of Industrial Science and Technology, Japan Chemical Innovation InstituteInventors: Kazuo Soga, Michihiko Asai, Yasuzo Suzuki, Akira Miyazawa, Kenji Tsuchihara, Masahide Murata, Hiroyuki Ozaki, Masanao Kawabe, Yoshifumi Fukui, Jizhy Jin, Hideaki Hagihara, Toshio Kase
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Patent number: 6614469Abstract: It is detected whether an automobile is running in a direction departing from a traffic lane, has already departed from the lane, or is running in a direction recovering from departure, by mounting on the automobile a steering angle detecting device for detecting an actual steering angle based on steering wheel operation of a driver, a television camera for taking pictures of the lane and a computer for processing the pictures taken by the television camera. The television camera is used to take pictures of markers on the lane while the automobile is running on the lane, and video signals are input into the computer.Type: GrantFiled: January 10, 2000Date of Patent: September 2, 2003Assignee: Japan as represented by Director General of Agency of Industrial Science and TechnologyInventors: Shin Kato, Sadayuki Tsugawa
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Patent number: 6610872Abstract: A polysilane is produced by subjecting a trihydrosilane to hydrogenative condensation in the presence of a titanium or zirconim complex catalyst having a first group selected from a dialkylaminoalkylcyclopentadienyl group, an &agr;-[(dialkylamino)alkyl]indenyl group and a &bgr;-[(dialkylamino)alkyl]indenyl group and a second group selected from a cyclopentadienyl group and a pentamethylcyclopentadienyl group. The above dialkylaminoalkyl group may be replaced by a branched alkyl group. The zirconium complexes are novel compounds.Type: GrantFiled: August 7, 2000Date of Patent: August 26, 2003Assignee: Director-General of Agency of Industrial Science and TechnologyInventors: Nami Choi, Shun-ya Onozawa, Toshiyasu Sakakura, Masato Tanaka
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Patent number: 6596076Abstract: There is disclosed an apparatus and method that appear to alter the effects of gravity by generating a magnetic field that causes an upward/downward magnetic force to act on a substance in a container. This offsets or adds to the downward force of gravity, to simulate a low-gravitational or excess-gravitational environment inside the substance.Type: GrantFiled: June 30, 1998Date of Patent: July 22, 2003Assignees: Director-General of Agency of Industrial Science and TechnologyInventor: Nobuko Wakayama
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Patent number: 6592436Abstract: A tool for grinding and polishing diamond and a method for polishing diamond in which a single crystal diamond, a diamond thin film, a sintered diamond compact and the like can be polished at low temperatures without causing cracks, fractures or degradation in quality therein. The tool and method provide a polishing operation which is easy to accomplish, provides stable polishing quality, and provides decreased costs while maintaining stable grinder performance. The grinder is formed of a main component which is an intermetallic compound consisting of one kind or more of elements selected from the group of Al, Cr, Mn, Fe, Co, Ni, Cu, Ru, Rh, Pd, Os, Ir and Pt and one kind or more of elements selected from the group of Ti, V, Zr, Nb, Mo, Hf, Ta and W. The diamond polishing method includes pushing the above stated grinder against the diamond, and rotating or moving the grinder relative to the diamond while keeping the portion of the diamond subjected to polishing at room temperature.Type: GrantFiled: May 4, 2000Date of Patent: July 15, 2003Assignees: Japan as represented by Director General of Agency of Industrial Science and Technology, Applied Diamond Inc.Inventors: Toshihiko Abe, Hitoshi Hashimoto, Shu-Ichi Takeda
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Patent number: 6582941Abstract: The present invention relates to the Schizochytrium genus SR21 strain and a microorganism belonging to the same species as does said SR21 strain or having substantially the same fungological properties as does said SR21 strain, the said SR21 strain and microorganism having the ability to produce the (n-3) series of docosahexaenoic acid (DHA) and the (n-6) series of docosapentaenoic acid (DPA), and the invention also relates to a process for preparing the (n-3) series of DHA and the (n-6) series of DPA utilizing said microorganisms. The microorganisms according to the present invention are superior in their proliferation character and their propensity to produce fat, and have the ability to produce the (n-3) series of DHA and the (n-6) series of DPA very well. Accordingly, it is possible to effectively produce the (n-3) series of DHA and/or the (n-6) series of DPA, which are useful in the fields of foods and pharmaceuticals, using the microorganisms according to the present invention.Type: GrantFiled: December 29, 1997Date of Patent: June 24, 2003Assignees: Japan as represented by Director-General of Agency of Industrial Science and Technology, Suntory LimitedInventors: Toshihiro Yokochi, Toro Nakahara, Takanori Higashihara, Satohiro Tanaka, Toshiaki Yaguchi
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Patent number: 6497762Abstract: A method of fabricating a crystal thin plate of a substance capable of forming a crystal, wherein a molten layer of the substance formed on a support is cooled in the atmosphere of an inert gas or in vacuum at a rate of 10-300° C. per second under a micro-gravity environment to solidify and crystallize the molten layer. The cooling is performed by contacting a portion of the support with a cooling medium.Type: GrantFiled: March 3, 1999Date of Patent: December 24, 2002Assignee: Director-General of Agency of Industrial Science and TechnologyInventors: Takeshi Okutani, Hideki Minagawa, Yoshinori Nakata, Hideaki Nagai, Masaaki Suzuki, Takashi Tsurue, Yoshiho Ito
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Patent number: 6493957Abstract: A ball step gauge includes a gauge framework that is H-shaped in cross-section and has a horizontal frame. A plurality of holes are formed at predetermined intervals in the horizontal frame in an axial direction of the horizontal frame. A plurality of grooves are formed around each of the holes. A plurality of balls are inserted under pressure in the holes, with centers of the balls existing on a neutral axis of moment of inertia of an area of the gauge framework. Since the ball intervals are less liable to change, the ball step gauge can be used as a reliable standard gauge for calibrating coordinate measuring machines.Type: GrantFiled: December 29, 2000Date of Patent: December 17, 2002Assignee: Japan as represented by Director General of Agency of Industrial Science and TechnologyInventors: Toshiyuki Takatsuji, Sonko Osawa, Tomizo Kurosawa, Hironori Noguchi
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Patent number: 6455649Abstract: A catalyst comprising an organoaluminum compound and a vanadium chelate compound having the lability to cause olefins to undergo living coordination polymerization is contacted with a terminal diolefin to obtain a catalyst for living polymer production. When the above contact is:conducted in the presence of a cycloolefin or an internal olefin, the yield of a living polymer can be improved. By modifying all ends of the living polymer obtained, a telechelic olefin polymer is obtained in which all the polymer chains are modified with functional groups.Type: GrantFiled: March 3, 2000Date of Patent: September 24, 2002Assignees: Japan as represented by Director General of Agency of Industrial Science and Technology, Japan Chemical Innovation InstituteInventors: Yoshihumi Fukui, Masahide Murata, Kazuo Soga, Michihiko Asai, Yasuzou Suzuki, Akira Miyazawa, Kenji Tsuchihara, Hiroyuki Ozaki, Masanao Kawabe, Naoya Kishi
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Patent number: 6443225Abstract: The present invention discloses a heat transfer changeover switch capable of effecting or cutting off positively heat transfer. The switch requires no contact or separation of a solid contact of a switch piece, is easily incorporated in a fine electronic device and generates no heat or vibration during a switch operation. The switch includes a heat pipe having a pipe for storing a heating medium therein disposed between a hot heat source and a cold heat source. A heating medium supplying/discharging device is provided for supplying/discharging the heating medium to and from the pipe. Heat transfer between the hot heat source and the cold heat source via the heat pipe is effected or cut off by using the heating medium supplying/discharging device that changes over between supply and discharge of the heating medium to and from the pipe.Type: GrantFiled: May 17, 2000Date of Patent: September 3, 2002Assignee: Director General of Agency of Industrial Science and TechnologyInventors: Akihiro Nakanou, Masao Shiraishi
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Patent number: 6409565Abstract: A field emission cathode capable of emitting electrons under a low voltage. Lead-out electrodes are formed on an insulating layer and openings are formed at a lamination between the insulating layer and each of the lead-out electrodes. Emitters each are arranged in each of the openings. The insulating layer is provided on a lower surface thereof with a photoresist layer modified by heating. The modified photoresist layer is electrically connected through a resistive layer to a cathode electrode. The cathode electrode is formed in a pattern on a cathode substrate made of glass or the like. The emitters each are constituted by a distal end of each of projections of the modified photoresist layer exposed from the insulating layer. The photoresist is modified by heating, resulting in being provided with electrical conductivity and exhibiting stable electron emitting characteristics under a low voltage.Type: GrantFiled: May 25, 1999Date of Patent: June 25, 2002Assignees: Futaba Denshi Kogyo Kabushiki Kaisha, Director General Agency of Industrial Science and Technology, Ministry of International Trade & IndustryInventors: Shigeo Itoh, Junji Itoh, Seigo Kanemaru
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Patent number: 6407228Abstract: A simple and efficient method is proposed for the preparation of a &bgr;-lactam compound such as 1-phenyl-4-ethoxy-2-azetidinone which can be produced by mixing an isocyanate compound such as phenyl isocyanate and a vinyl ether compound such as ethyl vinyl ether and heating the mixture at a moderate temperature under a superatmospheric pressure of up to 12000 atmospheres.Type: GrantFiled: September 12, 1995Date of Patent: June 18, 2002Assignee: Japan as represented by Director General of Agency of Industrial Science and TechnologyInventors: Yoichi Taguchi, Akihiro Oishi, Isao Shibuya, Tohru Tsuchiya
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Patent number: 6403846Abstract: A composition containing less than 95 mol % of a trihydrofluorinated saturated hydrocarbon represented by the following formula (I) Rf1—R1—Rf2 (I) (wherein R1 represents a carbon chain in which CHF and CH2 are bound, and Rf1 and Rf2 are bound to each other to form a ring by a perfluoroalkylene chain of 2 to 4 carbon atoms) and the balance of a tetrahydrofluorinated saturated hydrocarbon having the same carbon number and the same carbon structure as the trihydrofluorinated saturated hydrocarbon, as represented by the following formula (II) Rf1—R2—Rf2 (II) (wherein R2 represents a carbon chain in which CH2 and CH3 are bound, and Rf1 and Rf2 are as defined above) is provided as a composition containing, in a high proportion, trihydrofluorocarbon, a hydrofluorocarbon (HFC) known to have a small global heating coefficient, which has less influence on the global environment, shows less toxicity to animals, and is chemically stable.Type: GrantFiled: February 3, 2000Date of Patent: June 11, 2002Assignees: Japan as Represented by Director General of Agency of Industrial Science and Technology, Nippon Zeon Co., Ltd.Inventors: Akira Sekiya, Toshirou Yamada, Takashi Uruma, Tatsuya Sugimoto
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Patent number: 6383403Abstract: A substrate to be etched is subjected to dry etching by using a dry etching gas containing a perfluorocycloolefin while a plasma with a high density region of at least 1010/cm3 is generated. As the perfluorocycloolefin, those having 3 to 8 carbon atoms, especially 4 to 6 carbon atoms are preferably used.Type: GrantFiled: April 30, 1999Date of Patent: May 7, 2002Assignees: Japan as represented by the Director General of the Agency of Industrial Science and Technology, The Mechanical Social Systems Foundation, Electronic Industries Association of Japan, Nippon Zeon Co., Ltd.Inventors: Akira Sekiya, Toshiro Yamada, Kuniaki Goto, Tetsuya Takagaki
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Patent number: 6362712Abstract: Magnets comprising main magnets formed by arranging a single main magnet or plural main magnets, and auxiliary magnets for uniformalizing the magnetic force of the main magnets in a predetermined space. The magnets uniformalize the magnetic force in space.Type: GrantFiled: February 13, 2001Date of Patent: March 26, 2002Assignees: Japan Science and Technology Corporation, Japan as represented by Director General of National Reseacrh Institute for Metals, Japan as represented by Director General of Agency of Industrial Science and TechnologyInventors: Tsukasa Kiyoshi, Hitoshi Wada, Nobuko Wakayama