Patents Assigned to General Regeneratives Holdings, Inc.
  • Methods for promoting protection and regeneration of bone marrow using CXCL9 and anti-CXCL9 antibodies
    Patent number: 8367052
    Abstract: CXCL9 promotes bone marrow regeneration, increases peripheral white blood cells, and increases survival if administered prior to treatment of a subject with chemotherapeutic drugs such as 5-FU or radiotherapy. Similar effects are obtained by administering an anti-CXCL9 antibody following chemotherapy or radiotherapy. Compositions and methods are presented for the treatment of cancer and bone marrow diseases.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: February 5, 2013
    Assignee: General Regeneratives Holdings Inc.
    Inventors: Wei Han, Huili Lu
  • Methods for protecting and regenerating bone marrow using CXCR3 agonists and antagonists
    Patent number: 7943131
    Abstract: CXCR3 agonists, including natural CXCR3 ligands, promote bone marrow regeneration, increase peripheral white blood cells, and increase survival if administered prior to treatment of a subject with chemotherapy or radiotherapy. Similar effects are obtained by administering an CXCR3 antagonists following chemotherapy radiotherapy. Compositions and methods are presented for the treatment of cancer and bone marrow diseases.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: May 17, 2011
    Assignee: General Regeneratives Holdings, Inc.
    Inventors: Wei Han, Huili Lu, Di Xiang