Abstract: The present invention provides polypeptides comprising an immunogenic portion of a M. vaccae protein and DNA molecules encoding such polypeptides, together with methods for their use in the diagnosis and treatment of mycobacterial infection. Methods for enhancing the immune response to an antigen including administration of M. vaccae culture filtrate, delipidated M. vaccae cells or delipidated and deglycolipidated M. vaccae cells are also provided.
Type:
Grant
Filed:
June 11, 1998
Date of Patent:
December 12, 2000
Assignee:
Genesis Researth and Development Corporation Limited