Abstract: Limited rotation, micro-lens scanning of DNA arrays, microscope slides, biological materials, etc., is performed by arcuate and translational motion. A scanning system includes an objective lens located on a low moment of inertia oscillating arm, which provides optical coupling to a light source or a light detector arranged for transmission, reflection, or fluorescence microscopy.
Abstract: A fluid deposit assembly mounted on a carrier for depositing minute drops of fluid at selected locations upon a substrate, comprising a deposit element having an exposed tip of diameter of 0.3 mm or less constructed and arranged to carry and deposit drops of fluid upon the substrate, stable lateral reference surfaces or surface portions exposed for engagement by the deposit element, the surfaces or surface portions being constructed and arranged to prevent X, Y displacement of the deposit element relative to the carrier when the deposit element is urged thereagainst and design for urging the deposit element against the reference surfaces or surface portions at least at the time that the deposit element approaches a substrate to deposit a fluid drop. The reference surfaces or surface portions and the design for urging are cooperating to precisely position the deposit tip in a precisely desired position as it contacts the substrate.
The deposit element is shown as the tip of an axially moveable pin.
Type:
Grant
Filed:
July 24, 1998
Date of Patent:
August 7, 2001
Assignee:
Genetic Microsystems, Inc.
Inventors:
James W. Overbeck, Peter T. Flowers, Jean I. Montagu, Myles L. Mace, Peter Honkanen
Abstract: For enabling precise operation of an oscillating device, such as a galvanometric optical scanner, a capacitive position transducer is provided with strategically located internal capacitive fiducial features that interact with the armature of the transducer beyond the central range of excursion of the transducer, typically beyond the normal operating range of the device. Electric pulses obtained at instants of interaction with the fiducials enable determination of position drift caused e.g. by change in environmental conditions. The pulses can be detected by simple circuits to produce recalibration of the amplitude and null position of the instrument on an automatic or elective basis.
Type:
Grant
Filed:
June 4, 1999
Date of Patent:
April 17, 2001
Assignee:
Genetic Microsystems, Inc.
Inventors:
Jean I. Montagu, Peter Honkanen, Nathan K. Weiner