Patents Assigned to Genetics Institue, LLC
  • Antibodies against CTLA4
    Patent number: 7034121
    Abstract: The invention provides an antibody-toxic moiety conjugates comprising an antibody that specifically recognizes a molecule expressed on the surface of a T cell which is expressed only on T cells and is only expressed transiently on T cells upon T cell activation. Preferably, the T cell molecule is CTLA4. The invention further provides anti-CTLA4 antibodies and humanized forms thereof.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: April 25, 2006
    Assignee: Genetics Institue, LLC
    Inventors: Beatriz M. Carreno, Clive Wood, Katherine Turner, Mary Collins, Gary S. Gray, Donna Morris, Denise O'Hara, Paul R. Hinton, Naoya Tsurushita