Patents Assigned to GENETRONICS
  • Electroporation-enhanced inhibition of vascular neointimal hyperplasia
    Publication number: 20020183684
    Abstract: The present invention provides methods for inhibiting or preventing hyperplastic intimal growth by intravascular administration of a composition comprising heparin, or a derivative thereof in conjunction with at least one electric pulse having sufficient strength and duration to cause electroporation of the cells lining the blood vessel. Such treatment inhibits or prevents hyperplastic intimal growth in vessels, such as arteries, as compared with a non-electroporated vessel to which the heparin, or derivative thereof, is administered.
    Type: Application
    Filed: June 12, 2002
    Publication date: December 5, 2002
    Applicant: GENETRONICS
    Inventors: Nagendu B. Dev, Gunter A. Hofmann, Sukhendu B. Dev, Dietmar P. Rabussay