Patents Assigned to GENKYOTEX
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 10772891
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: September 15, 2020
    Assignee: GENKYOTEX SUISSE SA
    Inventors: Patrick Page, Mike Orchard, Benoit Laleu, Francesca Gaggini
  • IMMUNOGENIC COMPOSITION COMPRISING CYAA-DERIVED POLYPEPTIDE PROMOTING A TH1/TH17-ORIENTED IMMUNE RESPONSE
    Publication number: 20190307875
    Abstract: The invention relates to the use of a polypeptide derived from the adenylate cyclase of a Bordetella sp. (CyaA-derived polypeptide) by deletion of a segment of at least 93 amino acid residues, in particular a polypeptide derived from CyaA of Bordetella pertussis, as an immunomodifying antigen of the TH1/TH17-oriented immune response in an immunogenic composition. The invention relates to a vaccine candidate comprising such CyaA-derived polypeptide, either in an acellular immunogenic composition for active immunization against a condition causally related to the infection of a host by Bordetella sp. or in a combination composition encompassing said acellular immunogenic composition.
    Type: Application
    Filed: December 22, 2017
    Publication date: October 10, 2019
    Applicants: GENKYOTEX, SERUM INSTITUTE OF INDIA PRIVATE LIMITED
    Inventors: Rémi PALMANTIER, Yolande MISSERI, Caroline DIVEU-SADER, Sunil GAIROLA, Manish GAUTAM, Harish RAO, Umesh SHALIGRAM
  • Amido thiadiazole derivatives as NADPH oxidase inhibitors
    Patent number: 10130619
    Abstract: The present invention is related to amino thiazole derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: November 20, 2018
    Assignee: GENKYOTEX SUISSE SA
    Inventors: Peter Machin, Andrew Sharpe, Christopher James Lock, Mark S. Chambers, Alastair Hodges, Vivienne Allen, John M. Ellard
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 9974791
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: May 22, 2018
    Assignee: GENKYOTEX SUISSE SA
    Inventors: Patrick Page, Mike Orchard, Benoit Laleu, Francesca Gaggini
  • Pyrazoline dione derivatives as NADPH oxidase inhibitors
    Patent number: 9394306
    Abstract: The present invention is related to pyrazoline dione derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: July 19, 2016
    Assignee: GENKYOTEX SA
    Inventors: Patrick Page, Francesca Gaggini, Benoît Laleu
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 9096588
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: August 4, 2015
    Assignee: GENKYOTEX SA
    Inventors: Patrick Page, Mike Orchard, Benoit Laleu, Francesca Gaggini
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 9073919
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: July 7, 2015
    Assignee: GENKYOTEX SA
    Inventors: Patrick Page, Mike Orchard, Laetitia Fioraso-Cartier, Bianca Mottironi
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 9012449
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: April 21, 2015
    Assignee: Genkyotex SA
    Inventors: Patrick Page, Mike Orchard, Benoit Laleu, Francesca Gaggini
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 9006238
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: April 14, 2015
    Assignee: Genkyotex SA
    Inventors: Patrick Page, Mike Orchard, Benoit Laleu, Francesca Gaggini
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 8940760
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: July 5, 2013
    Date of Patent: January 27, 2015
    Assignee: Genkyotex SA
    Inventors: Patrick Page, Mike Orchard, Benoit Laleu, Francesca Gaggini
  • Pyrazolo piperidine derivatives as NADPH oxidase inhibitors
    Patent number: 8865758
    Abstract: The present invention is related to pyrazolo piperidine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: October 21, 2014
    Assignee: Genkyotex SA
    Inventors: Patrick Page, Benoît Laleu, Francesca Gaggini, Mike Orchard
  • Pyrazolo piperidine derivatives as NADPH oxidase inhibitors
    Patent number: 8748456
    Abstract: The present invention is related to pyrazolo piperidine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: June 10, 2014
    Assignee: Genkyotex SA
    Inventors: Patrick Page, Benoît Laleu, Francesca Gaggini, Mike Orchard
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 8481562
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: July 9, 2013
    Assignee: Genkyotex SA
    Inventors: Patrick Page, Mike Orchard, Benoit Laleu, Francesca Gaggini
  • PYRAZOLO PYRIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS
    Publication number: 20130158027
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Application
    Filed: January 31, 2013
    Publication date: June 20, 2013
    Applicant: GENKYOTEX SA
    Inventor: GENKYOTEX SA
  • PYRAZOLO PYRIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS
    Publication number: 20130143879
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Application
    Filed: January 31, 2013
    Publication date: June 6, 2013
    Applicant: GENKYOTEX SA
    Inventor: Genkyotex Sa
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 8455486
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: June 4, 2013
    Assignee: Genkyotex SA
    Inventors: Patrick Page, Mike Orchard, Benoit Laleu, Francesca Gaggini
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 8455485
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: June 4, 2013
    Assignee: Genkyotex SA
    Inventors: Patrick Page, Mike Orchard, Benoit Laleu, Francesca Gaggini
  • Pyrazolo Pyridine Derivatives as NADPH Oxidase Inhibitors
    Publication number: 20130123256
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Application
    Filed: January 4, 2013
    Publication date: May 16, 2013
    Applicant: GENKYOTEX SA
    Inventor: Genkyotex Sa
  • Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
    Patent number: 8389518
    Abstract: The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Grant
    Filed: March 20, 2008
    Date of Patent: March 5, 2013
    Assignee: Genkyotex SA
    Inventors: Patrick Page, Mike Orchard, Laetitia Fioraso-Cartier, Bianca Mottironi
  • Pyrazolo Piperidine Derivatives as NADPH Oxidase Inhibitors
    Publication number: 20120316380
    Abstract: The present invention is related to pyrazolo piperidine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
    Type: Application
    Filed: February 17, 2011
    Publication date: December 13, 2012
    Applicant: GENKYOTEX SA
    Inventors: Patrick Page, Benoît Laleu, Francesca Gaggini, Mike Orchard