Patents Assigned to Genomine, Inc.
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Patent number: 8278058Abstract: Disclosed herein are a composition and a kit for diagnosing renal cell carcinoma. The composition and kit employ, as a renal cell carcinoma marker, nicotinamide N-methyltransferase, L-plastin, secretagogin, NM23A, CapG, which is an actin regulatory protein, and/or C4a anaphylatoxin.Type: GrantFiled: August 6, 2008Date of Patent: October 2, 2012Assignees: DCD Inc., Genomine, Inc.Inventors: Dong Su Kim, Nam Hoon Cho, Hyung Jin Na, Young Deuk Choi, Jae Ho Jang, Hye-Kyung Kim, Mo Yoel Park, Won Man Park, Tae-hoon Kim, Dong Hee Lee, Kyung Mok Park
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Patent number: 8003340Abstract: Disclosed herein a method and a kit for fractioning/isolating phosphoproteins. Calcium ions, barium ions, cobalt ions and molybdenum ions are bound specifically to phosphoproteins to form metal-phosphoprotein complexes. They can be easily precipitated with precipitants including sulfates, citrates, bicarbonates and carbonates.Type: GrantFiled: June 20, 2008Date of Patent: August 23, 2011Assignees: DCD Inc., Genomine, Inc.Inventors: Dong Su Kim, Hyung Jin Na, Jae Ho Jang, Hye-Kyung Kim, Mo Yoel Park
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Patent number: 7795501Abstract: A novel protein, ORE 15, responsible for the regulation of plant leaf longevity is disclosed. Also, a gene encoding the protein ORE15 is disclosed. The protein and gene can be used in the regulation of plant leaf longevity, including delayed senescence, growth promotion, leaf weight, an size increase.Type: GrantFiled: August 31, 2005Date of Patent: September 14, 2010Assignees: Genomine, Inc., Postech FoundationInventors: Hong-gil Nam, Jin-hee Kim, Hye-ryun Woo
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Patent number: 7728193Abstract: The present invention relates to a novel protein interacting with phytochromes and use thereof, and more particularly, to a polypeptide having either an amino acid sequence set forth in SEQ ID NO: 4 or an amino acid sequence having at least 70% with said amino acid sequence, and use thereof. The polypeptide interacts with phytochromes A and B, and the TPR domain present at the N-terminal region of the polypeptide is involved in the interaction. Also, a PP2A catalytic domain (PP2Ac) having phosphatase activity is present at the C-terminal region of the polypeptide. The polypeptide can be used as a phosphatase, and is useful in the production of plants sensitive to light signal transduction. Furthermore, the TPR domain present in the polypeptide is useful in the production of dwarf plants.Type: GrantFiled: February 28, 2005Date of Patent: June 1, 2010Assignees: Genomine Inc., Postech FoundationInventors: Hong-Gil Nam, Jong-Sang Ryu, Pyung-Ok Lim, Ja-Choon Koo
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Publication number: 20090133153Abstract: The present invention discloses a polypeptide participating in pyridoxine biosynthesis, a polynucleotide coding the polypeptide and those uses. Particularly, this present invention discloses a polypeptide participating in pyridoxine biosynthesis, a polynucleotide coding the polypeptide, a method for inducing plant growth inhibition, a method for screening a compound inducing plant growth inhibition, and composition for inducing plant growth inhibition which comprises the compound obtained by the screening method.Type: ApplicationFiled: February 18, 2005Publication date: May 21, 2009Applicant: Genomine, IncInventors: Dong-hee Lee, Tae-Hoon Kim, In-taek Hwang, Kwang-yun Oho
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Publication number: 20080235826Abstract: The present invention relates to a novel protein interacting with phytochromes and use thereof, and more particularly, to a polypeptide having either an amino acid sequence set forth in SEQ ID NO: 4 or an amino acid sequence having at least 70% with said amino acid sequence, and use thereof. The polypeptide interacts with phytochromes A and B, and the TPR domain present at the N-terminal region of the polypeptide is involved in the interaction. Also, a PP2A catalytic domain (PP2Ac) having phosphatase activity is present at the C-terminal region of the polypeptide. The polypeptide can be used as a phosphatase, and is useful in the production of plants sensitive to light signal transduction. Furthermore, the TPR domain present in the polypeptide is useful in the production of dwarf plants.Type: ApplicationFiled: February 28, 2005Publication date: September 25, 2008Applicants: Genomine Inc., Poatech FoundationInventors: Hong-Gil Nam, Jong-Sang Ryu, Pyung-Ok Lim, Ja-Choon Koo
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Publication number: 20080216197Abstract: Disclosed herein are a polypeptide having a pyridoxine biosynthesis-related function, a polypeptide encoding the same, and uses thereof.Type: ApplicationFiled: February 1, 2006Publication date: September 4, 2008Applicants: Genomine, Inc., Korean Research Instittute Of Chemcial TechnologyInventors: Dong-hee Lee, In-taek Hwang, Kwang-yun Cho, Tae-hoon Kim
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Patent number: 7217855Abstract: The present invention relates to a gene regulating flowering time and a method for regulating flowering time in plants using the same. More particularly, the present invention relates to a COG gene having nucleotide sequence represented by SEQ ID No: 1 which is isolated from Arabidopsis thaliana, and a method for delaying flowering time of plants by overexpressing the gene, or for inducing early flowering by repressing an expression of the gene. The COG gene and the COG protein expressed therefrom according to the present invention are useful for improvement of flowering-associated character of plants, and for identification of flowering-associated genes or proteins in other plants, etc.Type: GrantFiled: August 22, 2002Date of Patent: May 15, 2007Assignees: Postech Foundation, Genomine, Inc.Inventors: Don-Ha Park, Hong-Gil Nam, Pyung-Ok Lim
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Patent number: 7141720Abstract: The present invention relates to a transcription factor of a plant, AtSIZ, induced by osmotic stress; a gene encoding the transcription factor; and a method for enhancing resistance to stress of a plant by using the gene. The AtSIZ protein isolated from Arabidopsis thaliana is a polypeptide, which contains a C3H-type zinc finger motif and acts as a transcription regulation factor activating transcription of genes related to stress response of a plant. Therefore, a plant with the enhanced resistance to osmotic stress can be produced by over expressing the AtSIZ gene in the plant through transforming recombinant plasmid containing AtSIZ gene into a plant and consequently, the productivity of the plant can be increased.Type: GrantFiled: March 9, 2001Date of Patent: November 28, 2006Assignee: Genomine, Inc.Inventors: Inhwan Hwang, Hai Lan Piao
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Patent number: 7060875Abstract: The present invention relates to a gene regulating leaf longevity of plants and a method for regulating the longevity of plants using the same. More particularly, it relates to a ORE7 gene regulating leaf longevity of plants which has a nucleotide sequence represented by SEQ ID NO: 1, and to a method for regulating the longevity of plants, in which the ORE7 gene is introduced into the plants and overexpressed, thereby delaying senescence of the plants. Plants can be transformed with ORE7 gene according to the present invention, so that the longevity of the plants is extended, thereby improving productivity and storage efficiency of the plants. Furthermore, the ORE7 gene and an ORE7 protein expressed therefrom according to the present invention are useful for studies of senescence mechanisms, and for identification of senescence-associated genes or senescence inhibitory substances, in plants.Type: GrantFiled: August 22, 2002Date of Patent: June 13, 2006Assignees: Postech Foundation, Genomine, Inc.Inventors: Pyung-Ok Lim, Hong-Gil Nam, Sung-Whan Cho
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Patent number: 6444805Abstract: The oral vaccine of the present invention containing the HPV like particles is produced in edible transgenic plants and then administered through the consumption of the edible portion of those plants or after the purification of the particles. A DNA sequence encoding one of the HPV capsid proteins is isolated, inserted into the plasmid which comprises a plant-specific promoter and a gene for a selection marker, and then transferred to plant cells to give transgenic plants. Since the gene is expressed in a portion of the plants, the oral vaccine of the present invention can be produced in an inexpensive manner and administered in a simple method.Type: GrantFiled: February 24, 2000Date of Patent: September 3, 2002Assignee: Genomine, Inc.Inventors: Ulk Sohn, Hong Gil Nam, Deok Hoon Park, Kuk Hyun Kim