Patents Assigned to Genopoietic
  • Methods and compositions for producing viral particles
    Patent number: 6489142
    Abstract: The invention concerns methods and constructs for producing retroviral particles, in vitro, ex vivo or in vivo. It also concerns the use of said methods and constructs for transferring nucleic acids into cells. More particularly, the invention concerns a composition comprising the whole set of genetic elements required for constituting a retroviral particle, incorporated in one or several recombinant adenoviruses defective for all or part of the regions E1 and E4 at least (adenoviral/retroviral chimeric vectors).
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: December 3, 2002
    Assignees: Aventis Pharma S.A., Genopoietic
    Inventors: Christophe Torrent, Patrice Yeh, Michel Perricaudet, David Klatzmann, Jean-Loup Salzmann