Abstract: The present invention is directed to compounds, compositions and methods for treating or preventing viral infections, in particular, HCV in human patients or other animal hosts.
Type:
Grant
Filed:
October 28, 2011
Date of Patent:
May 20, 2014
Assignees:
RFS Pharma, LLC, Genoscience
Inventors:
Jerome Courcambeck, Philippe Halfon, Mourad Bouzidi, Steven J. Coats, Richard Anthony Whitaker
Abstract: The present invention is directed to compounds, compositions and methods for treating or preventing viral infections, in particular, HCV in human patients or other animal hosts.
Type:
Application
Filed:
October 28, 2011
Publication date:
May 24, 2012
Applicants:
GENOSCIENCE, RFS Pharma, LLC
Inventors:
Jerome Courcambeck, Philippe Halfon, Mourad Bouzidi, Steven J. Coats, Richard Anthony Whitaker
Abstract: The present invention relates to novel hepatitis C virus (“HCV”) protease inhibitors or other flavivirus protease inhibitors having the general structure (I) or (II), pharmaceutical compositions containing one or more such inhibitors, methods for preparing such inhibitors, uses of these compounds to treat hepatitis C and related disorders together with their use for their activity towards NS3 serine protease, intermediary compounds for the method of preparation of said compounds and screening methods. The invention specifically discloses novel chemical compounds as inhibitors of the HCV serine protease.
Type:
Application
Filed:
October 9, 2003
Publication date:
June 29, 2006
Applicant:
GENOSCIENCE
Inventors:
Philippe Halfon, Chalom Sayada, Jean-Marc Feryn, Regis Perbost, Frederic Garzino, Michel Camplo, Jerome Courcambeck, Gerard Pepe