Patents Assigned to GENOSCO Inc.
  • Selective inhibitors of ROCK1 and ROCK2 protein kinases and uses thereof
    Patent number: 12064426
    Abstract: The present invention relates to novel substituted bicyclic derivatives that can inhibit Rho-kinases and/or Rho-kinase mediated phosphorylation of myosin light chain phosphates, compositions comprising the derivatives, methods for preparing the derivatives, and methods for using the derivatives and/or compositions.
    Type: Grant
    Filed: January 5, 2022
    Date of Patent: August 20, 2024
    Assignee: GENOSCO Inc.
    Inventors: Wongil Lee, William G. Devine, R. Bruce Diebold, So Young Hwang, Yunggeun Choi, Yan Liu, Sang-Ae Seung, Miyong Yong, Sewon Kim, Jaekyoo Lee, Jong Sung Koh