Abstract: Provided are an improved EGFR antibody or a functional segment thereof, comprising an engineered heavy chain and light chain. Specifically, the antibody is an engineered whole human-source monoclonal antibody. Also provided is a method for manufacturing said whole human-source antibody and usage of the antibody in the manufacture of medicines used for the treatment of tumors.
Type:
Grant
Filed:
October 6, 2015
Date of Patent:
May 9, 2017
Assignees:
GENRIX (SHANGHAI) BIOPHARMACERTICAL CO., LTD., BIOEX THERAPEUTICS INC.
Inventors:
Jie Liu, Zhuobing Zhang, Jikuan Shan, Wei Suo
Abstract: Provided are an improved EGFR antibody or a functional segment thereof, comprising an engineered heavy chain and light chain. Specifically, the antibody is an engineered whole human-source monoclonal antibody. Also provided is a method for manufacturing said whole human-source antibody and usage of the antibody in the manufacture of medicines used for the treatment of tumors.