Patents Assigned to GENTEGRA LLC
  • Patent number: 10160997
    Abstract: The present invention provides compositions useful for biomolecule storage comprising a water soluble inorganic compound, a stabilizer, or a combination thereof. The present invention also provides methods of using the compositions of the invention to store biomolecules in the dry state and in solution, as well as sample carriers and kits comprising compositions of the invention.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: December 25, 2018
    Assignee: GenTegra LLC
    Inventors: Michael Hogan, Michael Saghbini, David Wong
  • Patent number: 9840731
    Abstract: The invention provides compositions and methods for preserving a biological material—such as a protein, a nucleic acid or a biological sample, or any combination thereof—in a substantially water-free, nonionic or ionic organic solvent. Improved preservation, including for example the stability and/or the solubility of the biological material in the substantially water-free fluid medium, is achieved with compositions comprising one or more substances (e.g., an antioxidant) described in the disclosure, and/or a metal salt. The biological material is soluble and stable, and retains its function and activity, when it is preserved in the substantially water-free fluid medium at ambient temperature or higher for extended periods of time. Therefore, the composition comprising the biological material does not need to be refrigerated or frozen during shipping or storage.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 12, 2017
    Assignee: Gentegra, LLC
    Inventor: Michael Hogan
  • Patent number: 9637513
    Abstract: The present invention provides compositions useful for biomolecule storage comprising a water soluble inorganic compound, a stabilizer, or a combination thereof. The present invention also provides methods of using the compositions of the invention to store biomolecules in the dry state and in solution, as well as sample carriers and kits comprising compositions of the invention.
    Type: Grant
    Filed: January 14, 2015
    Date of Patent: May 2, 2017
    Assignee: GenTegra LLC
    Inventors: Michael Hogan, Michael Saghbini, David Wong
  • Publication number: 20150267245
    Abstract: The invention provides compositions and methods for preserving a biological material—such as a protein, a nucleic acid or a biological sample, or any combination thereof—in a substantially water-free, nonionic or ionic organic solvent. Improved preservation, including for example the stability and/or the solubility of the biological material in the substantially water-free fluid medium, is achieved with compositions comprising one or more substances (e.g., an antioxidant) described in the disclosure, and/or a metal salt. The biological material is soluble and stable, and retains its function and activity, when it is preserved in the substantially water-free fluid medium at ambient temperature or higher for extended periods of time. Therefore, the composition comprising the biological material does not need to be refrigerated or frozen during shipping or storage.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 24, 2015
    Applicant: GenTegra, LLC
    Inventor: Michael Hogan
  • Patent number: 8951719
    Abstract: The present invention provides compositions useful for biomolecule storage comprising a water soluble inorganic compound, a stabilizer, or a combination thereof. The present invention also provides methods of using the compositions of the invention to store biomolecules in the dry state and in solution, as well as sample carriers and kits comprising compositions of the invention.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: February 10, 2015
    Assignee: Gentegra, LLC.
    Inventors: Michael Hogan, Michael Saghbini, David Wong, Chunnian Shi
  • Publication number: 20140227686
    Abstract: The present invention provides compositions and methods that enable the stabilization and storage of samples by contacting a sample with an assembly of particles, and reducing the water activity level of the contacted sample. By reducing the water activity level of the sample, the assembly of particles minimizes the degradation of the sample. Stabilizers may or may not be added to the assembly of particles to further minimize the degradation of the sample. Subsequently to storage in the assembly of particles, the samples are recoverable by eluting the assembly of particles with a fluid solution. In one embodiment, the entire assembly of particles will dissolve into the solution. In another embodiment, only part of the assembly of particles will dissolve into the solution. The assembly of particles provides the advantage that while it is porous, it comprises non-porous particulate material.
    Type: Application
    Filed: April 16, 2014
    Publication date: August 14, 2014
    Applicant: GENTEGRA LLC
    Inventors: Michael Saghbini, Michael Hogan, Chunnian Shi, Brian Dalby, David Wong